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Active axial eye motion tracking by extended range, closed loop OPD-locked white light interferometer for combined confocal/en face optical coherence tomography imaging of the human eye fundus in vivo

Cucu, Radu G. and Hathaway, Mark W. and Podoleanu, Adrian Gh. and Rosen, Richard B. (2009) Active axial eye motion tracking by extended range, closed loop OPD-locked white light interferometer for combined confocal/en face optical coherence tomography imaging of the human eye fundus in vivo. In: Optical Coherence Tomography and Coherence Techniques IV. Proceedings of SPIE . SPIE. ISBN 978-0-8194-7648-7. (doi:10.1117/12.831807) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1117/12.831807

Abstract

We report an active tracking device based on white light coherence ranging using a spectrally interrogated Michelson interferometer, which is used to monitor and correct for the axial displacement of the eye and head of the subject in a confocal scanning ophthalmoscope/ en face OCT system (SLO/OCT). The Nyquist limit range of the spectrometer in the tracking interferometer is ~5.4 mm, which is adequate for monitoring the axial position of axially extended layered objects like the human eye fundus. Both the tracking and imaging interferometers share the eye interface optics and the sample and also an optical path (OPD) changing device in the reference (fast voice coil mounted retroreflector), that keeps them locked at constant OPD values. As a consequence, the sensitivity of the tracking interferometer is not affected by the spectrometer sensitivity roll-off with increased OPD and mirror term ambiguity tracking errors close to OPD = 0 are eliminated. Moreover, the axial tracking range is only limited by the voice coil stage travel range. A real time data acquisition processor board is used to digitize the spectrometer signal and calculate the correction signal applied to the voice coil with an update time better than 5 ms. We demonstrate axial motion corrected combined confocal/ en face OCT imaging of the human eye fundus in vivo.

Item Type: Book section
DOI/Identification number: 10.1117/12.831807
Additional information: Unmapped bibliographic data: C7 - 73721R [EPrints field already has value set] LA - English [Field not mapped to EPrints] J2 - Progr. Biomed. Opt. Imaging Proc. SPIE [Field not mapped to EPrints] AD - Applied Optics Group, School of Physical Sciences, University of Kent, Canterbury, CT2 7NH, United Kingdom [Field not mapped to EPrints] AD - OTI, OPKO, Toronto, M3J 3E5, Canada [Field not mapped to EPrints] AD - Advanced Retinal Imaging Center, New York Eye and Ear Infirmary, New York City, NY 10003, United States [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints] A4 - Optical Society of America; The Society of Photo-Optical Instrumentation Engineers (SPIE); Photonics4Life-European Network of Excellence for Biophotonics; Air Force Office of Scientific Research [Field not mapped to EPrints] C3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE [Field not mapped to EPrints]
Uncontrolled keywords: Axial eye motion, Closed loop OPD-locked tracking interferometer, Combined confocal scanning opthalmoscopy/en face OCT, Real-time processing, Spectral interrogation, Axial eye motion, Closed loops, Confocal scanning, Realtime processing, Spectral interrogation, Light, Michelson interferometers, Spectrometers, Spectrometry, Tomography
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 14 Jul 2015 15:33 UTC
Last Modified: 29 Jul 2019 13:30 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49453 (The current URI for this page, for reference purposes)
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