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Ex vivo optical coherence tomography imaging of larynx tissues using a forward-viewing resonant fiber-optic scanning endoscope

Cernat, R. and Zhang, Y.Y. and Bradu, A. and Tatla, T. and Tadrous, P.J. and Li, X.D. and Podoleanu, A.Gh. (2012) Ex vivo optical coherence tomography imaging of larynx tissues using a forward-viewing resonant fiber-optic scanning endoscope. In: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI. Proceedings of SPIE . SPIE. ISBN 978-0-8194-8856-5. (doi:10.1117/12.911209) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1117/12.911209

Abstract

A miniature endoscope probe for forward viewing in a 50 kHz swept source optical coherence tomography (SS-OCT) configuration was developed. The work presented here is an intermediate step in our research towards in vivo endoscopic laryngeal cancer screening. The endoscope probe consists of a miniature tubular lead zirconate titanate (PZT) actuator, a single mode fiber (SMF) cantilever and a GRIN lens, with a diameter of 2.4 mm. The outer surface of the PZT actuator is divided into four quadrants that form two pairs of orthogonal electrodes (X and Y). When sinusoidal waves of opposite polarities are applied to one electrode pair, the PZT tube bends transversally with respect to the two corresponding quadrants, and the fiber optic cantilever is displaced perpendicular to the PZT tube. The cantilever's resonant frequency was found experimentally as 47.03 Hz. With the GRIN lens used, a lateral resolution of � 13 μm is expected. 2D en face spiral scanning pattern is achieved by adjusting the phase between the pairs of X and Y electrodes drive close to 90 degrees. Furthermore, we demonstrate the imaging capability of the probe by obtaining B-scan images of diseased larynx tissue and compare them with those obtained in a 1310 nm SS-OCT classical non-endoscopic system. © 2012 SPIE.

Item Type: Book section
DOI/Identification number: 10.1117/12.911209
Uncontrolled keywords: Endoscopy; Optical coherence tomography; Resonant fiber optic endoscope
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 16 Jul 2015 11:21 UTC
Last Modified: 26 Jul 2019 10:39 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49379 (The current URI for this page, for reference purposes)
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