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Dynamic focus optical coherence tomography: Feasibility for improved basal cell carcinoma investigation

Nasiri-Avanaki, M.R. and Aber, A. and Hojjatoleslami, S.A. and Sira, M. and Schofield, J.B. and Jones, C. and Podoleanu, A.Gh. (2012) Dynamic focus optical coherence tomography: Feasibility for improved basal cell carcinoma investigation. In: Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X. Proceedings of SPIE . SPIE. ISBN 978-0-8194-8868-8. (doi:10.1117/12.912081) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1117/12.912081

Abstract

Basal cell carcinoma (BCC) is the most common form of skin cancer. To improve the diagnostic accuracy, additional non-invasive methods of making a preliminary diagnosis have been sought. We have implemented an En-Face optical coherence tomography (OCT) for this study in which the dynamic focus was integrated into it. With the dynamic focus scheme, the coherence gate moves synchronously with the peak of confocal gate determined by the confocal interface optics. The transversal resolution is then conserved throughout the depth range and an enhanced signal is returned from all depths. The Basal Cell Carcinoma specimens were obtained from the eyelid a patient. The specimens under went analysis by DF-OCT imaging. We searched for remarkable features that were visualized by OCT and compared these findings with features presented in the histology slices.

Item Type: Book section
DOI/Identification number: 10.1117/12.912081
Uncontrolled keywords: Basal cell carcinoma (BCC), dynamic focus scheme, histology images, Optical coherence tomography (OCT), skin diseases diagnosis, Basal cell carcinoma, Depth range, Diagnostic accuracy, histology images, Histology slices, Noninvasive methods, Skin cancers, Transversal resolution, Biomolecules, Cytology, Dermatology, Histology, Noninvasive medical procedures, Optical tomography, Tissue, Cells
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 16 Jul 2015 11:15 UTC
Last Modified: 26 Jul 2019 10:40 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49374 (The current URI for this page, for reference purposes)
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