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Quantitative evaluation of scattering in optical coherence tomography skin images using the extended Huygens-Fresnel theorem

Avanaki, M.R.N., Podoleanu, Adrian G.H., Schofield, J.B., Jones, C., Sira, M., Liu, Y., Hojjatoleslami, Ali (2013) Quantitative evaluation of scattering in optical coherence tomography skin images using the extended Huygens-Fresnel theorem. Applied Optics, 52 (8). pp. 1574-1580. ISSN 1559-128X. (doi:10.1364/AO.52.001574) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1364/AO.52.001574

Abstract

An optical properties extraction algorithm is developed based on enhanced Huygens-Fresnel light propagation theorem, to extract the scattering coefficient of a specific region in an optical coherence tomography (OCT) image. The aim is to quantitatively analyze the OCT images. The algorithm is evaluated using a set of phantoms with different concentrations of scatterers, designed based on Mie theory. The algorithm is then used to analyze basal cell carcinoma and healthy eyelid tissues, demonstrating distinguishable differences in the scattering coefficient between these tissues. In this study, we have taken advantage of the simplification introduced by the utilization of a dynamic focus OCT system. This eliminates the need to deconvolve the reflectivity profile with the confocal gate profile, as the sensitivity of the OCT system is constant throughout the axial range. © 2013 Optical Society of America.

Item Type: Article
DOI/Identification number: 10.1364/AO.52.001574
Uncontrolled keywords: Algorithms, Histology, Optical properties, Tissue, Axial range, Basal cell carcinoma, Dynamic focus, Optical properties extraction algorithms, Quantitative evaluation, Reflectivity profiles, Scattering co-efficient, Skin images, Optical tomography, algorithm, computer assisted diagnosis, cytology, devices, epiluminescence microscopy, human, image enhancement, image quality, light, optical coherence tomography, photometry, procedures, radiation scattering, skin, article, computer assisted diagnosis, cytology, epiluminescence microscopy, equipment, image enhancement, methodology, optical coherence tomography, photometry, skin, Algorithms, Dermoscopy, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Light, Nephelometry and Turbidimetry, Phantoms, Imaging, Scattering, Radiation, Skin, Tomography, Optical Coherence, Algorithms, Dermoscopy, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Light, Nephelometry and Turbidimetry, Phantoms, Imaging, Scattering, Radiation, Skin, Tomography, Optical Coherence
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 16 Jul 2015 09:35 UTC
Last Modified: 29 May 2019 14:47 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49345 (The current URI for this page, for reference purposes)
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