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Investigation of basal cell carcinoma using dynamic focus optical coherence tomography

Avanaki, M.R.N., Hojjatoleslami, Ali, Sira, M., Schofield, J.B., Jones, C., Podoleanu, Adrian G.H. (2013) Investigation of basal cell carcinoma using dynamic focus optical coherence tomography. Applied Optics, 52 (10). pp. 2116-2124. ISSN 1559-128X. (doi:10.1364/AO.52.002116) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1364/AO.52.002116

Abstract

Optical coherence tomography (OCT) is becoming a popular modality for skin tumor diagnosis and assessment of tumor size and margin status. We conducted a number of imaging experiments on periocular basal cell carcinoma (BCC) specimens using an OCT configuration. This configuration employs a dynamic focus (DF) procedure where the coherence gate moves synchronously with the peak of the confocal gate, which ensures better signal strength and preservation of transversal resolution from all depths. A DF-OCT configuration is used to illustrate morphological differences between the BCC and its surrounding healthy skin in OCT images. The OCT images are correlated with the corresponding histology images. To the best of our knowledge, this is the first paper to look at DF-OCT imaging in examining periocular BCC. © 2013 Optical Society of America.

Item Type: Article
DOI/Identification number: 10.1364/AO.52.002116
Uncontrolled keywords: Diagnosis, Tumors, Basal cell carcinoma, Dynamic focus, Histology images, Imaging experiments, Margin status, Signal strengths, Skin tumor, Transversal resolution, Optical tomography, article, basal cell carcinoma, computer assisted diagnosis, equipment, equipment design, equipment failure, human, image enhancement, optical coherence tomography, optical instrumentation, pathology, reproducibility, sensitivity and specificity, skin tumor, basal cell carcinoma, computer assisted diagnosis, device failure analysis, devices, image enhancement, optical coherence tomography, pathology, skin tumor, Carcinoma, Basal Cell, Equipment Design, Equipment Failure Analysis, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Lenses, Reproducibility of Results, Sensitivity and Specificity, Skin Neoplasms, Tomography, Optical Coherence, Carcinoma, Basal Cell, Equipment Design, Equipment Failure Analysis, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Lenses, Reproducibility of Results, Sensitivity and Specificity, Skin Neoplasms, Tomography, Optical Coherence
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 16 Jul 2015 09:34 UTC
Last Modified: 29 May 2019 14:47 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49344 (The current URI for this page, for reference purposes)
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