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Imaging the eye fundus with real-time en-face spectral domain optical coherence tomography

Bradu, Adrian, Podoleanu, Adrian G.H. (2014) Imaging the eye fundus with real-time en-face spectral domain optical coherence tomography. Biomedical Optics Express, 5 (4). pp. 1233-1249. ISSN 2156-7085. (doi:10.1364/BOE.5.001233) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:49277)

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Real-time display of processed en-face spectral domain optical coherence tomography (SD-OCT) images is important for diagnosis. However, due to many steps of data processing requirements, such as Fast Fourier transformation (FFT), data re-sampling, spectral shaping, apodization, zero padding, followed by software cut of the 3D volume acquired to produce an en-face slice, conventional high-speed SD-OCT cannot render an en-face OCT image in real time. Recently we demonstrated a Master/Slave (MS)-OCT method that is highly parallelizable, as it provides reflectivity values of points at depth within an A-scan in parallel. This allows direct production of en-face images. In addition, the MS-OCT method does not require data linearization, which further simplifies the processing. The computation in our previous paper was however time consuming. In this paper we present an optimized algorithm that can be used to provide en-face MS-OCT images much quicker. Using such an algorithm we demonstrate around 10 times faster production of sets of en-face OCT images than previously obtained as well as simultaneous real-time display of up to 4 en-face OCT images of 200 � 200 pixels2 from the fovea and the optic nerve of a volunteer. We also demonstrate 3D and B-scan OCT images obtained from sets of MS-OCT C-scans, i.e. with no FFT and no intermediate step of generation of A-scans. © 2014 Optical Society of America.

Item Type: Article
DOI/Identification number: 10.1364/BOE.5.001233
Additional information: This is available as OPEN ACCESS by clicking on the URL.
Uncontrolled keywords: Algorithms, Data processing, Eye protection, Fast Fourier transforms, Optical tomography, Data linearization, Direct production, Fast fourier transformation (FFT), Optimized algorithms, Real time display, Reflectivity values, Spectral domain optical coherence tomographies, Spectral shaping, Three dimensional, A scan, algorithm, article, correlation analysis, eye fundus, human, image reconstruction, information processing, interferometry, master slave optical coherence tomography, signal processing, spectral domain optical coherence tomography
Subjects: Q Science > QC Physics > QC355 Optics
R Medicine > RE Ophthalmology
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Funders: European Research Council (
University College London (
Depositing User: Giles Tarver
Date Deposited: 09 Jul 2015 14:56 UTC
Last Modified: 17 Aug 2022 10:59 UTC
Resource URI: (The current URI for this page, for reference purposes)

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