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Towards simultaneous Talbot bands based optical coherence tomography and scanning laser ophthalmoscopy imaging

Marques, M.J., Bradu, Adrian, Podoleanu, Adrian G.H. (2014) Towards simultaneous Talbot bands based optical coherence tomography and scanning laser ophthalmoscopy imaging. Biomedical Optics Express, 5 (5). pp. 1428-1444. ISSN 2156-7085. (doi:10.1364/BOE.5.001428) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:49276)

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We report a Talbot bands-based optical coherence tomography (OCT) system capable of producing longitudinal B-scan OCT images and en-face scanning laser ophthalmoscopy (SLO) images of the human retina in-vivo. The OCT channel employs a broadband optical source and a spectrometer. A gap is created between the sample and reference beams while on their way towards the spectrometer's dispersive element to create Talbot bands. The spatial separation of the two beams facilitates collection by an SLO channel of optical power originating exclusively from the retina, deprived from any contribution from the reference beam. Three different modes of operation are presented, constrained by the minimum integration time of the camera used in the spectrometer and by the galvo-scanners' scanning rate: (i) a simultaneous acquisition mode over the two channels, useful for small size imaging, that conserves the pixel-to-pixel correspondence between them; (ii) a hybrid sequential mode, where the system switches itself between the two regimes and (iii) a sequential "on-demand" mode, where the system can be used in either OCT or SLO regimes for as long as required. The two sequential modes present varying degrees of trade-off between pixel-to-pixel correspondence and independent full control of parameters within each channel. Images of the optic nerve and fovea regions obtained in the simultaneous (i) and in the hybrid sequential mode (ii) are presented. ©2014 Optical Society of America.

Item Type: Article
DOI/Identification number: 10.1364/BOE.5.001428
Additional information: This is available as OPEN ACCESS by clicking on the URL.
Uncontrolled keywords: Eye protection, Pixels, Scanning, Spectrometers, Time switches, Broad-band optical sources, Dispersive elements, Integration time, Modes of operation, Reference beams, Scanning laser ophthalmoscopy, Simultaneous acquisition, Spatial separation, Optical tomography, article, fundus camera, human, optic nerve, optical coherence tomography, retina fovea, retina image, scanning laser ophthalmoscopy, spectrometer, talbot bands based optical coherence tomography
Subjects: Q Science > QC Physics > QC355 Optics
R Medicine > RE Ophthalmology
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Depositing User: Giles Tarver
Date Deposited: 10 Jul 2015 09:12 UTC
Last Modified: 17 Aug 2022 10:59 UTC
Resource URI: (The current URI for this page, for reference purposes)

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