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A CT-image-based framework for the holistic analysis of cortical and trabecular bone morphology

Gross, Thomas, Kivell, Tracy L., Skinner, Matthew M., Nguyen, N. Huynh, Pahr, Dieter H. (2014) A CT-image-based framework for the holistic analysis of cortical and trabecular bone morphology. Palaeontologia Electronica, 17 (3;33A). pp. 1-13. ISSN 1094-8074. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://palaeo-electronica.org/content/2014/889-hol...

Abstract

This study introduces a standardized framework for the holistic analysis of cortical and trabecular bone structure. This method, although applicable to all bones of the skeleton, is particularly useful for irregular-shaped or small bones for which the application of traditional methods has been especially challenging. Traditional analyses have quantified cortical or trabecular structure in only selected regions of a bone, such as single cross-sections of cortical bone or volumes of interest of trabecular structure in epiphyses. The proposed method improves on these traditional methods by visualizing and quantifying the internal bony structure throughout the entire bone and in user-defined anatomical subregions. Here, we describe and demonstrate the method using high-resolution microtomographic scans of a first metacarpal of an orangutan, gorilla, chimpanzee and human. Using automated morphological filters, the cortical bone is defined and extracted from the underlying trabecular structure to create two 3D models, one of the cortex and one of the trabecular bone that can be analysed separately. We test the sensitivity of the morphological parameters used to create these 3D models, demonstrating that the parameters defined here are robust and can provide accurate measures of cortical thickness, relative bone density, trabecular orientation, trabecular thickness and degree of anisotropy. This new, holistic method is able to reveal morphological and functional information about bone loading that is obscured or ignored using traditional methods, thus providing more informed interpretations of behaviour in extant and fossil taxa.

Item Type: Article
Uncontrolled keywords: cancellous bone; locomotion; hominoid; metacarpal; functional morphology
Subjects: Q Science
Divisions: Faculties > Social Sciences > School of Anthropology and Conservation > Biological Anthropology
Depositing User: Matthew Skinner
Date Deposited: 15 May 2015 12:19 UTC
Last Modified: 29 May 2019 14:34 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/48528 (The current URI for this page, for reference purposes)
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