Identification and sequence analysis of the homologues of the herpes-simplex virus type-1 glycoprotein-H in Marek's disease virus and the herpesvirus of turkeys

Scott, Simon D., Smith, GD, Ross, NLJ, Binns, MM (1993) Identification and sequence analysis of the homologues of the herpes-simplex virus type-1 glycoprotein-H in Marek's disease virus and the herpesvirus of turkeys. Journal of General Virology, 74 (6). pp. 1185-1190. ISSN 0022-1317. (doi:10.1099/0022-1317-74-6-1185) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1099/0022-1317-74-6-1185

Abstract

The glycoprotein H (gH) genes of two avian herpesviruses, Marek's disease virus and the herpesvirus of turkeys, have been cloned and sequenced and the coding regions found to be of 2439 and 2424 nucleotides respectively. The predicted primary polypeptide products of these open reading frames are 813 and 808 amino acids and correspond to M(r)s of 90 800 and 91 100. Both amino acid sequences exhibit characteristic glycoprotein features such as hydrophobic signal and anchor sequences and potential sites for N-linked glycosylation. Polypeptide sequence comparison to the other eight available gH sequences revealed more similarity to the alphaherpesvirus subgroup than to either beta- or gamma-herpesviruses.

Item Type: Article
DOI/Identification number: 10.1099/0022-1317-74-6-1185
Subjects: Q Science > QR Microbiology > QR355 Virology
Divisions: Faculties > Sciences > Medway School of Pharmacy
Depositing User: Simon Scott
Date Deposited: 03 Dec 2017 14:09 UTC
Last Modified: 29 May 2019 13:52 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/45901 (The current URI for this page, for reference purposes)
Scott, Simon D.: https://orcid.org/0000-0002-8290-0461
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