Skip to main content

Functionalization of cycloolefin polymer surfaces by plasma-enhanced chemical vapour deposition: Comprehensive characterization and analysis of the contact surface and the bulk of aminosiloxane coatings

Gubala, V., Gandhiraman, R.P., Volcke, C., Doyle, C., Coyle, C., James, B., Daniels, S., Williams, D.E. (2010) Functionalization of cycloolefin polymer surfaces by plasma-enhanced chemical vapour deposition: Comprehensive characterization and analysis of the contact surface and the bulk of aminosiloxane coatings. Analyst, 135 (6). pp. 1375-1381. ISSN 0003-2654. (doi:10.1039/b924692d)

PDF - Pre-print
Download (1MB) Preview
[img]
Preview
Official URL
http://dx.doi.org/10.1039/b924692d

Abstract

The surface science of bioassay devices is of great importance in the development of modern diagnostic platforms. The quality of surface is one of the most important elements of the device, often governing the background response, hence controlling the sensitivity of an assay. Detailed surface characterization and analysis are imperative for the preparation of reproducible coatings with desired properties. We performed a comprehensive characterization of 3-aminopropyl-triethoxysilane films prepared under two different deposition conditions on COP slides. Two sets of slides were prepared, by exposing them to plasma reaction for 30 seconds (A30 slide) and 4 minutes (A4 slide). While the variations in the deposition conditions seemed very subtle, the use of several powerful analytical tools helped us to reveal some fundamental differences between the studied films in terms of binding capacity, swelling and adhesion. Overall, the A30 films, with a thickness of 5.12 nm, showed up to 40% higher binding capacity and 25% better adhesion than the thicker A4 coatings (28.15 nm). Upon contact with aqueous media, a significant change was observed in terms of surface roughness. The A30 slides outperformed A4 slides, resulting in smoother surface, which is an important parameter for biomolecule immobilisation. The use of the techniques described in this article is aimed to set new standards for the characterization and analysis of the substrate surface of the future diagnostic devices. © The Royal Society of Chemistry 2010.

Item Type: Article
DOI/Identification number: 10.1039/b924692d
Additional information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Analyst [Field not mapped to EPrints] C2 - 20396819 [Field not mapped to EPrints] AD - Biomedical Diagnostics Institute (BDI), Dublin City University, Collins Avenue, Glasnevin, Dublin 9, Ireland [Field not mapped to EPrints] AD - Research Centre in Physics of Matter and Radiation (PMR), University of Namur (FUNDP), 61, rue de Bruxelles, B-5000 Namur, Belgium [Field not mapped to EPrints] AD - Research Centre for Surface and Materials Science, Department of Chemical and Materials Engineering, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand [Field not mapped to EPrints] AD - National Centre for Plasma Science and Technology, Dublin City University, Collins Avenue, Glasnevin, Dublin 9, Ireland [Field not mapped to EPrints] AD - MacDiarmid Institute for Advanced Materials and Nanotechnology, Department of Chemistry, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled keywords: cycloalkane derivative, polymer, siloxane, article, atomic force microscopy, chemistry, gas, interferometry, mass spectrometry, methodology, surface property, X ray photoelectron spectroscopy, Cycloparaffins, Gases, Interferometry, Mass Spectrometry, Microscopy, Atomic Force, Photoelectron Spectroscopy, Polymers, Siloxanes, Surface Properties
Divisions: Faculties > Sciences > Medway School of Pharmacy
Depositing User: Vladimir Gubala
Date Deposited: 14 Dec 2017 20:53 UTC
Last Modified: 29 May 2019 13:41 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/45239 (The current URI for this page, for reference purposes)
Gubala, V.: https://orcid.org/0000-0001-6301-3632
  • Depositors only (login required):

Downloads

Downloads per month over past year