Molesti, Eleonora, Wright, Edward, Terregino, Calogero, Rahman, Rafat, Cattoli, Giovanni, Temperton, Nigel J. (2014) Multiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies. In: International Meeting on Emerging Diseases and Surveillance (IMED 2014), 31 Oct - 03 Nov 2014, Vienna, Austria. (Unpublished) (doi:Poster 22.053) (KAR id:43721)
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Abstract
Purpose: The increased number of outbreaks of H5 and H7 LPAI and
The continuous rapid evolution of these subtypes and the emergence
Retroviral pseudotypes bearing influenza haemagglutinin (HA) and
for sensitive, readily standardized influenza serological assays.
that are directed against both influenza H5 and H7 HA. This assay
two antigenically distinct HAs in the same serum/plasma sample thus
acquired from valuable sera.
with a monovalent H5N2 vaccine, chickens vaccinated with a bivalent
were evaluated in the pseudotype assay (simple and multiplex format).
correlated strongly with data obtained by HI assay. We show that pseudotypes
and following multiple rounds of freeze-thaw.
utility for in-field serosurveillance and vaccine studies in resource-limited
regions worldwide.
Item Type: | Conference or workshop item (Poster) |
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DOI/Identification number: | Poster 22.053 |
Subjects: | Q Science > QR Microbiology > QR355 Virology |
Divisions: | Faculties > Sciences > Medway School of Pharmacy |
Depositing User: | Nigel Temperton |
Date Deposited: | 27 Oct 2014 12:58 UTC |
Last Modified: | 23 Jan 2020 04:08 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/43721 (The current URI for this page, for reference purposes) |
Temperton, Nigel J.: | ![]() |
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