A new model for ductal carcinoma in situ suggests strategies for treatment

Gullick, William J. (2002) A new model for ductal carcinoma in situ suggests strategies for treatment. Breast Cancer Research, 4 (5). pp. 176-178. ISSN 1465-5411 . (Full text available)

PDF (A New Model for Ductal Carcinoma )
Download (36kB)
Official URL


Human ductal carcinoma in situ (DCIS) of the breast is now diagnosed quite frequently, due largely to the introduction of mammographic screening. It has been shown in a cell culture system that activation of c-erbB-2, but not the epidermal growth factor receptor, results in a DCIS-like phenotype. Since overexpression of c-erbB-2 occurs in 60% of DCIS, this suggests that it could be a target for treatment in this disease.

Item Type: Article
Additional information: Free full-text article in PubMed Central and on Breast Cancer Research.
Uncontrolled keywords: ductal carcinoma in situ, growth factor receptor, tyrosine kinase inhibitor
Subjects: Q Science
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences > Biomedical Research Group
Depositing User: Bill Gullick
Date Deposited: 04 Sep 2008 14:11
Last Modified: 22 Apr 2014 15:30
Resource URI: https://kar.kent.ac.uk/id/eprint/3986 (The current URI for this page, for reference purposes)
  • Depositors only (login required):


Downloads per month over past year