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Clinical value of epidermal growth factor receptor expression in primary breast cancer

Rampaul, Raj, Pinder, S.E., Nicholson, R.I., Gullick, William J., Robertson, J.F., Ellis, Ian O. (2005) Clinical value of epidermal growth factor receptor expression in primary breast cancer. Advances in Anatomic Pathology, 12 (5). pp. 271-273. ISSN 1072-4109. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

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EGFR expression in primary breast cancer has been extensively investigated for its prognostic and predictive value. However overall there is no consensus on its potential to guide such prognostication. This is largely because of the great heterogeneity in study designs and methods used to assay the EGFR protein. The impetus to standardize such studies is much needed as there are now several tyrosine kinase inhibitors directed against the EGF receptor and phase II trials are showing significant promise.

Item Type: Article
Uncontrolled keywords: Adenocarcinoma/diagnosis/*metabolism Breast Neoplasms/diagnosis/*metabolism Female Gene Expression Regulation, Neoplastic Humans Predictive Value of Tests Prognosis Receptor, Epidermal Growth Factor/genetics/*metabolism
Subjects: Q Science
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculties > Sciences > School of Biosciences > Biomedical Research Group
Depositing User: Bill Gullick
Date Deposited: 30 Aug 2008 21:33 UTC
Last Modified: 28 May 2019 13:39 UTC
Resource URI: (The current URI for this page, for reference purposes)
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