The effect of exercise on behavioural and psychological symptoms of dementia: the EVIDEM-E randomised controlled clinical trial

Lowery, David and Cerga-Pashoja, Arlinda and Iliffe, Steve and Thuné-Boyle, Ingela and Griffin, Mark and Lee, James and Bailey, Alex and Bhattacharya, Rahul and Warner, James (2013) The effect of exercise on behavioural and psychological symptoms of dementia: the EVIDEM-E randomised controlled clinical trial. International Journal of Geriatric Psychiatry, . ISSN 0885-6230 . (doi:https://doi.org/10.1002/gps.4062) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1002/gps.4062

Abstract

Objective The objective of this study is to evaluate the effectiveness of a simple dyadic (person with dementia and their main carer) exercise regimen as a therapy for the behavioural and psychological symptoms of dementia. Method A two arm, pragmatic, randomised, controlled, single-blind, parallel-group trial of a dyadic exercise regimen (individually tailored walking regimen designed to become progressively intensive and last between 20–30 min, at least five times per week).Community-dwelling individuals with ICD-10 confirmed dementia with the following: clinically significant behavioural and psychological symptoms, a carer willing and able to co-participate in the exercise regimen, and no physical conditions or symptoms that would preclude exercise participation were invited by mental health or primary care services into the study. Results One hundred and thirty-one dyads were recruited to this study. There was no significant difference in Behavioural and Psychological Symptoms as measured by the Neuropsychiatric Inventory at week 12 between the group receiving the dyadic exercise regimen and those that did not (adjusted difference in means (intervention minus control) = −1.53, p = 0.6, 95% CI [−7.37, 4.32]). There was a significant between-group difference in caregiver's burden as measured by the Zarit Caregiver Burden Inventory at week 12 (OR = 0.18, p = 0.01, CI [0.05, 0.69]) favouring the exercise group. Conclusions This study found that regular simple exercise does not appear to improve the behavioural and psychological symptoms of dementia, but did seem to attenuate caregiver burden. Further study to improve exercise uptake are needed.

Item Type: Article
Additional information: Trial Registration: ISRCTN01423159 Online Version of Record published before inclusion in an issue
Uncontrolled keywords: trial; dementia; exercise; physical activity; behavioural and psychological symptoms
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RC Internal medicine > RC952 Geriatrics
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies
Depositing User: Tony Rees
Date Deposited: 13 Dec 2013 15:49 UTC
Last Modified: 30 Jun 2016 12:50 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/37623 (The current URI for this page, for reference purposes)
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