Skip to main content

Optimised anaesthesia to reduce Post Operative Cognitive Decline (POCD) in older patients undergoing elective surgery, a randomized controlled trial

Ballard, Clive G., Jones, Emma L., Gague, Nathan, Aarsland, Dag, Nilsen, Odd Bjarte, Saxby, Brian K., Lowery, David, Corbett, Anne, Wesnes, Keith, Katsaiti, Eirini, and others. (2012) Optimised anaesthesia to reduce Post Operative Cognitive Decline (POCD) in older patients undergoing elective surgery, a randomized controlled trial. PLoS ONE, . ISSN 1932-6203. (doi:10.1371/journal.pone.0037410) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:36617)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1371/journal.pone.0037410

Abstract

Background

The design was a prospective cohort study with a nested randomised, controlled intervention trial, using intra-operative BiSpectral index and cerebral oxygen saturation monitoring to enable optimisation of anaesthesia depth and cerebral oxygen saturation in older adults undergoing surgery.

Results

POCD is common and persistent in older adults following surgery. The results of the nested RCT indicate the potential benefits of intra-operative monitoring of anaesthetic depth and cerebral oxygenation as a pragmatic intervention to reduce post-operative cognitive impairment.

Item Type: Article
DOI/Identification number: 10.1371/journal.pone.0037410
Additional information: Controlled-Trials.com ISRCTN39503939
Subjects: R Medicine > RC Internal medicine > RC321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RC Internal medicine > RC952 Geriatrics
R Medicine > RD Surgery
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies
Depositing User: Tony Rees
Date Deposited: 20 Nov 2013 09:41 UTC
Last Modified: 29 May 2019 11:25 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/36617 (The current URI for this page, for reference purposes)
  • Depositors only (login required):