Langdon, Peter E., Harley, C.W., McLean, John (1997) Increased beta adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonergic depletion. Developmental Brain Research, 102 (2). pp. 291-293. (doi:10.1016/S0165-3806(97)00090-4) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:36123)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1016/S0165-3806(97)00090-4 |
Abstract
It was hypothesized that 5-HT2 receptors in the olfactory bulb prime the bulbar response to a beta adrenoceptor mediated unconditioned stimulus (UCS) during odor preference learning in 1-week-old rat pups. The ability of 4 mg/kg of isoproterenol + stroking and 6 mg/kg of isoproterenol + no stroking to induce normal odor preference learning in pups depleted of bulbar 5-HT in the present study supports the hypothesis. The inverted-U curve relation between UCS strength and learning also appears to occur within the bulb.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1016/S0165-3806(97)00090-4 |
| Uncontrolled keywords: | Adrenergic receptor; 5-HT2 receptor; Isoproterenol; Neonate; Inverted-U curve |
| Subjects: | H Social Sciences > H Social Sciences (General) |
| Divisions: | Divisions > Division for the Study of Law, Society and Social Justice > School of Social Policy, Sociology and Social Research > Tizard |
| Depositing User: | Peter Langdon |
| Date Deposited: | 11 Nov 2013 12:29 UTC |
| Last Modified: | 16 Nov 2021 10:13 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/36123 (The current URI for this page, for reference purposes) |
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