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Increased beta adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonergic depletion

Langdon, Peter E., Harley, C.W., McLean, John (1997) Increased beta adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonergic depletion. Developmental Brain Research, 102 (2). pp. 291-293. (doi:10.1016/S0165-3806(97)00090-4) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:36123)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1016/S0165-3806(97)00090-4

Abstract

It was hypothesized that 5-HT2 receptors in the olfactory bulb prime the bulbar response to a beta adrenoceptor mediated unconditioned stimulus (UCS) during odor preference learning in 1-week-old rat pups. The ability of 4 mg/kg of isoproterenol + stroking and 6 mg/kg of isoproterenol + no stroking to induce normal odor preference learning in pups depleted of bulbar 5-HT in the present study supports the hypothesis. The inverted-U curve relation between UCS strength and learning also appears to occur within the bulb.

Item Type: Article
DOI/Identification number: 10.1016/S0165-3806(97)00090-4
Uncontrolled keywords: Adrenergic receptor; 5-HT2 receptor; Isoproterenol; Neonate; Inverted-U curve
Subjects: H Social Sciences > H Social Sciences (General)
Divisions: Divisions > Division for the Study of Law, Society and Social Justice > School of Social Policy, Sociology and Social Research > Tizard
Depositing User: Peter Langdon
Date Deposited: 11 Nov 2013 12:29 UTC
Last Modified: 16 Feb 2021 12:48 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/36123 (The current URI for this page, for reference purposes)
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