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The MOSAIC study - comparison of the Maudsley Model of Treatment for Adults with Anorexia Nervosa (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with anorexia nervosa or eating disorder not otherwise specified,anorexia nervosa type: study protocol for a randomized controlled trial

Schmidt, Ulrike, Ulrike, Beth, Lose, Anna, Kenyon, Martha, DeJong, Hannah, Broadbent, Hannah, Loomes, Rachel, Watson, Charlotte, Ghelani, Shreena, Serpell, Lucy, and others. (2013) The MOSAIC study - comparison of the Maudsley Model of Treatment for Adults with Anorexia Nervosa (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with anorexia nervosa or eating disorder not otherwise specified,anorexia nervosa type: study protocol for a randomized controlled trial. Trials, 14 (160). ISSN 1745-6215. (doi:10.1186/1745-6215-14-160)

Abstract

Background: Anorexia nervosa (AN) is a biologically based serious mental disorder with high levels of mortality

disease burden in terms of years of life lost through death or disability in young women. Psychotherapeutic

the illness. The treatment response in adults with a chronic form of the illness is poor and drop-out from treatment

extremely limited and there is no leading treatment. There is therefore an urgent need to develop more effective

Related Conditions (MOSAIC) is to evaluate the efficacy and cost effectiveness of two outpatient treatments for

with Anorexia Nervosa (MANTRA).

groups (MANTRA or SSCM). All participants receive 20 once-weekly individual therapy sessions (with 10 extra weekly

optional access to a dietician and extra sessions involving a family member or a close other. Body weight, eating

the course of treatment and across a one year follow up period. The primary outcome measure is body mass index

Discussion: This multi-center study provides a large sample size, broad inclusion criteria and a follow-up period.

controlled trial and the psychopathology of AN. These issues are discussed.

anorexia nervosa and related conditions.

Item Type: Article
DOI/Identification number: 10.1186/1745-6215-14-160
Uncontrolled keywords: Anorexia nervosa, Eating disorder not otherwise specified, Outpatient treatment, Randomized controlled trial, Cost effectiveness
Subjects: H Social Sciences
R Medicine > RC Internal medicine
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Personal Social Services Research Unit
Depositing User: R. Bass
Date Deposited: 11 Sep 2013 10:17 UTC
Last Modified: 06 Feb 2020 04:08 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/35171 (The current URI for this page, for reference purposes)
Beecham, Jennifer: https://orcid.org/0000-0001-5147-3383
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