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Viral Membrane Scission

Rossman, Jeremy S., Lamb, Robert A. (2013) Viral Membrane Scission. Annual Review of Cell and Developmental Biology, 29 . pp. 551-569. ISSN 1081-0706. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://www.annualreviews.org/doi/abs/10.1146/annur...

Abstract

Virus budding is a complex, multistep process in which viral proteins make specific alterations in membrane curvature. Many different viral proteins can deform the membrane and form a budding virion, but very few can mediate membrane scission to complete the budding process. As a result, enveloped viruses have developed numerous ways of facilitating membrane scission, including hijacking host cellular scission machinery and expressing their own scission proteins. These proteins mediate scission in very different ways, though the biophysical mechanics underlying their actions may be similar. In this review, we explore the mechanisms of membrane scission and the ways in which enveloped viruses use these systems to mediate the release of budding virions.

Item Type: Article
Subjects: Q Science > QR Microbiology > QR355 Virology
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Jeremy Rossman
Date Deposited: 21 Aug 2013 14:46 UTC
Last Modified: 29 May 2019 10:29 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/35000 (The current URI for this page, for reference purposes)
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