Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues

Foster, Helen A. and Griffin, Darren K. and Bridger, Joanna M. (2012) Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues. BMC Cell Biology, 13 (1). p. 30. ISSN 1471-2121. (doi:https://doi.org/10.1186/1471-2121-13-30) (Full text available)

PDF - Author's Accepted Manuscript
Download (1MB) Preview
[img]
Preview
Official URL
http://dx.doi.org/10.1186/1471-2121-13-30

Abstract

In interphase nuclei of a wide range of species chromosomes are organised into their own specific locations termed territories. These chromosome territories are non-randomly positioned in nuclei which is believed to be related to a spatial aspect of regulatory control over gene expression. In this study we have adopted the pig as a model in which to study interphase chromosome positioning and follows on from other studies from our group of using pig cells and tissues to study interphase genome re-positioning during differentiation. The pig is an important model organism both economically and as a closely related species to study human disease models. This is why great efforts have been made to accomplish the full genome sequence in the last decade.

Item Type: Article
Subjects: Q Science
Q Science > QL Zoology
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Darren Griffin
Date Deposited: 06 Jun 2013 08:31 UTC
Last Modified: 18 Jun 2014 09:09 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/34143 (The current URI for this page, for reference purposes)
  • Depositors only (login required):

Downloads

Downloads per month over past year