West Nile virus infection induces interferon signalling in human retinal pigment epithelial cells.

Cinatl, Jindrich and Michaelis, Martin and Fleckenstein, Corinna and Bauer, Gabriele and Kabicková, Hanka and Scholz, Martin and Rabenau, Holger F and Doerr, Hans Wilhelm (2006) West Nile virus infection induces interferon signalling in human retinal pigment epithelial cells. Investigative Ophthalmology and Visual Science, 47 (2). pp. 645-51. ISSN 0146-0404. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Abstract

In this study, the first cell culture model of ophthalmic WNV infection was developed and characterized in RPE cells, and the molecular mechanisms of WNV infection were studied. The data suggest that WNV induces a general antiviral state in RPE cells. This general antiviral state correlates with WNV-induced IFN signaling in retinal cells.

Item Type: Article
Subjects: Q Science > QR Microbiology > QR355 Virology
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Martin Michaelis
Date Deposited: 05 Jun 2013 20:51 UTC
Last Modified: 28 Apr 2014 13:22 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/34101 (The current URI for this page, for reference purposes)
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