The threat of avian influenza a (H5N1): part II: Clues to pathogenicity and pathology.

Cinatl, Jindrich and Michaelis, Martin and Doerr, Hans Wilhelm (2007) The threat of avian influenza a (H5N1): part II: Clues to pathogenicity and pathology. Medical Microbiology and Immunology, 196 (4). pp. 191-201. ISSN 1432-1831. (doi:https://doi.org/10.1007/s00430-007-0045-2) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1007/s00430-007-0045-2

Abstract

Among emerging and re-emerging infectious diseases, influenza constitutes one of the major threats to mankind. In this review series epidemiologic, virologic and pathologic concerns raised by infections of humans with avian influenza virus A/H5N1 are discussed. The second part focuses on experimental and clinical results, which give insights in the pathogenic mechanisms of H5N1 infection in humans. H5N1 is poorly transmitted to humans. However, H5N1-induced disease is very severe. More information on the role entry barriers, H5N1 target cells and on H5N1-induced modulation of the host immune response is needed to learn more about the determinants of H5N1 pathogenicity.

Item Type: Article
Subjects: Q Science > QR Microbiology > QR355 Virology
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Martin Michaelis
Date Deposited: 05 Jun 2013 21:04 UTC
Last Modified: 01 Jul 2014 15:46 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/34093 (The current URI for this page, for reference purposes)
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