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Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells.

Michaelis, Martin, Kleinschmidt, Malte C, Doerr, Hans Wilhelm, Cinatl, Jindrich (2007) Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells. Journal of Antimicrobial Chemotherapy, 60 (5). pp. 981-986. ISSN 0305-7453. (doi:10.1093/jac/dkm307) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1093/jac/dkm307

Abstract

These data suggest that minocycline-induced inhibition of JNK activation contributes to minocycline-induced inhibition of WNV replication and WNV-induced apoptosis. Minocycline is a clinically available, inexpensive and generally very well-tolerated drug. It could be readily evaluated for the treatment of humans with serious WNV infection.

Item Type: Article
DOI/Identification number: 10.1093/jac/dkm307
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Martin Michaelis
Date Deposited: 05 Jun 2013 21:14 UTC
Last Modified: 29 May 2019 10:14 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/34086 (The current URI for this page, for reference purposes)
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