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MAGD Trial-Memantine for Agitation in Alzheimer’s Dementia

Fox, Christopher, Boustani, Malaz, Crugel, Monica, Maidment, Ian D., Ballard, Clive G., Katona, Cornelius, Livingston, Gill, Adrian, T., Coulton, Simon, Macshane, R. and others. (2011) MAGD Trial-Memantine for Agitation in Alzheimer’s Dementia. In: Journal of the American Geriatrics Society. 59 (s1). S65-S66. (doi:10.1111/j.1532-5415.2011.03416.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1111/j.1532-5415.2011.03416.x

Abstract

OBJECTIVE: Does memantine improve agitation in dementia

SETTING: Nursing Homes

INTERVENTION: Memantine vs placebo

(CMAI), Neuro-Psychiatric Inventory (NPI), Severe Impairment

RESULTS:CMAI-there was no statistically significant difference

NPI-9 point difference between memantine vs placebo p=0.01

Agitation, disinhibition and irritability-p=0.001

of the percent change from baseline to week 12 p=0.02

about the contact with friends compared to the patients treated with

CONCLUSION:

agitation on the CMAI with memantine but the NPI reached signficance

was significant. Cognition and quality of life improved. We believe

patients with Alzheimer’s dementia

Item Type: Conference or workshop item (Paper)
DOI/Identification number: 10.1111/j.1532-5415.2011.03416.x
Additional information: AGS Annual meeting, Thursday 12 May 2011
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies
Depositing User: Simon Coulton
Date Deposited: 26 Jun 2012 14:27 UTC
Last Modified: 22 Jan 2020 04:04 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/29706 (The current URI for this page, for reference purposes)
Coulton, Simon: https://orcid.org/0000-0002-7704-3274
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