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Efficacy of Memantine for Agitation in Alzheimer’s Dementia: A Randomised Double-Blind Placebo Controlled Trial

Fox, Christopher, Crugel, Monica, Maidment, Ian D., Auestad, Bjorn Henrik, Coulton, Simon, Treloar, Adrian, Ballard, Clive G., Boustani, Malaz, Katona, Cornelius, Livingston, Gill and others. (2012) Efficacy of Memantine for Agitation in Alzheimer’s Dementia: A Randomised Double-Blind Placebo Controlled Trial. PLoS ONE, 7 (5). ISSN 1932-6203. (doi:10.1371/journal.pone.0035185)

Abstract

Background

Methods and Findings

Conclusions

Memantine did not improve significant agitation in people with in moderate-to-severe AD. Future studies are urgently needed to test other pharmacological candidates in this group and memantine for neuropsychiatric symptoms.

Item Type: Article
DOI/Identification number: 10.1371/journal.pone.0035185
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA421 Public health. Hygiene. Preventive Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies
Depositing User: Tony Rees
Date Deposited: 15 May 2012 13:04 UTC
Last Modified: 22 Jan 2020 04:04 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/29466 (The current URI for this page, for reference purposes)
Coulton, Simon: https://orcid.org/0000-0002-7704-3274
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