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Cytochrome bd confers nitric oxide resistance to Escherichia coli.

Mason, Maria G., Shepherd, Mark, Nicholls, Peter J., Dobbin, Paul S, Dodsworth, Kathryn S, Poole, Robert K, Cooper, Chris E (2009) Cytochrome bd confers nitric oxide resistance to Escherichia coli. Nature Chemical Biology, 5 (2). pp. 94-6. ISSN 1552-4450. (doi:10.1038/nchembio.135) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1038/nchembio.135

Abstract

The aerobic respiratory chain of Escherichia coli has two terminal quinol oxidases: cytochrome bo and cytochrome bd. Cytochrome bd was thought to function solely to facilitate micro-aerobic respiration. However, it has recently been shown to be overexpressed under conditions of nitric oxide (NO) stress; we show here that cytochrome bd is crucial for protecting E. coli cells from NO-induced growth inhibition by virtue of its fast NO dissociation rate.

Item Type: Article
DOI/Identification number: 10.1038/nchembio.135
Subjects: Q Science
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Mark Shepherd
Date Deposited: 01 Sep 2011 15:54 UTC
Last Modified: 29 May 2019 08:38 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/28101 (The current URI for this page, for reference purposes)
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