Mason, Maria G. and Shepherd, Mark and Nicholls, Peter J. and Dobbin, Paul S and Dodsworth, Kathryn S and Poole, Robert K and Cooper, Chris E (2009) Cytochrome bd confers nitric oxide resistance to Escherichia coli. Nature Chemical Biology, 5 (2). pp. 94-6. ISSN 1552-4450. (doi:https://doi.org/10.1038/nchembio.135) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)
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The aerobic respiratory chain of Escherichia coli has two terminal quinol oxidases: cytochrome bo and cytochrome bd. Cytochrome bd was thought to function solely to facilitate micro-aerobic respiration. However, it has recently been shown to be overexpressed under conditions of nitric oxide (NO) stress; we show here that cytochrome bd is crucial for protecting E. coli cells from NO-induced growth inhibition by virtue of its fast NO dissociation rate.
|Divisions:||Faculties > Sciences > School of Biosciences|
|Depositing User:||Mark Shepherd|
|Date Deposited:||01 Sep 2011 15:54 UTC|
|Last Modified:||14 Jul 2014 12:44 UTC|
|Resource URI:||https://kar.kent.ac.uk/id/eprint/28101 (The current URI for this page, for reference purposes)|