Skip to main content

Validation of the growth hormone (GH)-dependent marker method of detecting GH abuse in sport through the use of independent data sets

Erotokritou-Mulligan, Ioulietta, Bassett, Eryl E., Kniess, Astrid, Sonksen, Peter H., Holt, Richard I. G. (2007) Validation of the growth hormone (GH)-dependent marker method of detecting GH abuse in sport through the use of independent data sets. Growth Hormone & IGF Research, 17 (5). pp. 416-423. ISSN 1096-6374. (doi:10.1016/j.ghir.2007.04.013) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:2766)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1016/j.ghir.2007.04.013

Abstract

Context: The detection of exogenously administered growth hormone (GH) poses a formidable challenge but a detection method based on the measurement of two GH-dependent markers, IGF-I and type 3 pro-collagen (P-III-P) has been proposed. The measurement of multiple markers in conjunction with discriminant functions can improve the sensitivity and specificity of detection compared with single marker analysis.

Conclusions: The study provides further validation that the test proposed by GH-2000 based on IGF-I and P-III-P concentrations can be used to detect subjects receiving exogenous GH.

Item Type: Article
DOI/Identification number: 10.1016/j.ghir.2007.04.013
Uncontrolled keywords: growth hormone; sport; abuse; discriminant function; markers
Subjects: Q Science > QA Mathematics (inc Computing science)
Q Science > QH Natural history > QH301 Biology
Divisions: Faculties > Sciences > School of Mathematics Statistics and Actuarial Science > Statistics
Depositing User: Louise Dorman
Date Deposited: 24 Apr 2008 08:22 UTC
Last Modified: 28 May 2019 13:38 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/2766 (The current URI for this page, for reference purposes)
  • Depositors only (login required):