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Evolution of enzymes and pathways for the biosynthesis of cofactors

Holliday, Gemma L., Thornton, Janet M., Marquet, Andrée, Smith, Alison G., Rebeille, Fabrice, Mendel, Ralf, Schubert, Heidi L., Lawrence, Andrew D., Warren, Martin J. (2007) Evolution of enzymes and pathways for the biosynthesis of cofactors. Natural Product Reports, 24 (5). pp. 972-987. ISSN 0265-0568. (doi:10.1039/b703107f) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Abstract

The evolution of metabolic pathways is discussed with reference to the biosynthesis of a number of vitamins and cofactors. Retrograde and patchwork models are highlighted and their relevance to our knowledge of pathway processes and enzymes is examined. Pathway complexity is explained in terms of the acquisition of broad specificity enzymes

Item Type: Article
DOI/Identification number: 10.1039/b703107f
Subjects: Q Science > Q Science (General)
Divisions: Faculties > Sciences > School of Biosciences
Depositing User: Maureen Cook
Date Deposited: 18 Mar 2008 16:41 UTC
Last Modified: 23 Jan 2020 04:00 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/2277 (The current URI for this page, for reference purposes)
Warren, Martin J.: https://orcid.org/0000-0002-6028-6456
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