Stefaniak, M.H. and Tinardon, F. and Wallis, John D. (1997) A synthesis of alpha,alpha-disubstituted aryl-beta-ketoesters. Synlett (6). pp. 677-678. ISSN 0936-5214. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)
A generally applicable synthesis of alpha,alpha-disubstituted beta-ketoesters involving reaction of a substituted benzoyl chloride with methyl trimethylsilyl ketene acetal is described. Addition of boron trifluoride etherate is essential when the benzoyl chloride is nor substituted with a strongly electron withdrawing residue. The majority of experiments were conducted with the dimethylketene acetal but the process is equally applicable to the cyclohexaneketene acetal 5.
|Subjects:||Q Science > QD Chemistry|
|Divisions:||Faculties > Science Technology and Medical Studies > School of Physical Sciences|
|Depositing User:||T.J. Sango|
|Date Deposited:||12 May 2009 09:03|
|Last Modified:||12 May 2009 09:03|
|Resource URI:||https://kar.kent.ac.uk/id/eprint/17973 (The current URI for this page, for reference purposes)|