Synthetic approaches to macromolecular models for ion channel proteins

Azam, Farzana, Bladon, Christine M. (1998) Synthetic approaches to macromolecular models for ion channel proteins. Tetrahedron Letters, 39 (35). pp. 6377-6380. ISSN 0040-4039. (doi:10.1016/S0040-4039(98)01313-6) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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http://dx.doi.org/10.1016/S0040-4039(98)01313-6

Abstract

The synthesis of a branched peptide is described using a ligation strategy to couple two peptides one of which is fully deprotected while the other is in a protected form. The ligation step involves formation of a thioether bond by using the thiol of a cysteine on the deprotected sequence to displace bromide from a bromoacetyl moiety on the second peptide.

Item Type: Article
DOI/Identification number: 10.1016/S0040-4039(98)01313-6
Subjects: Q Science > QD Chemistry
Divisions: Faculties > Sciences > School of Physical Sciences
Depositing User: I. Ghose
Date Deposited: 04 Apr 2009 14:08 UTC
Last Modified: 28 May 2019 13:55 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/17557 (The current URI for this page, for reference purposes)
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