Skip to main content

Carbon-branched delta-tetrahydrofuran sugar amino acids (SAAs) as dipeptide isostere scaffolds

Simone, Michela L., Edwards, Alison A., Tranter, George E., Fleet, George W.J. Carbon-branched delta-tetrahydrofuran sugar amino acids (SAAs) as dipeptide isostere scaffolds. Tetrahedron, . ISSN 0040-4020. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:16775)

PDF (2008 Tetrahedron C-2 branched SAA monomers)
Language: English

Restricted to Repository staff only
Contact us about this Publication
[thumbnail of 2008 Tetrahedron C-2 branched SAA monomers]

Abstract

The synthesis of the first branched sugar amino acid (SAA) scaffolds [methyl (3R,4R,5R)-5-azidomethyl-

3-carboxylate] by an efficient intramolecular displacement of a highly hindered neopentyl triflate allows access to enantiopure THF derivatives which have carbon substituents.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Alison Edwards
Date Deposited: 29 Jun 2011 07:46 UTC
Last Modified: 16 Feb 2021 12:27 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/16775 (The current URI for this page, for reference purposes)
Edwards, Alison A.: https://orcid.org/0000-0002-4637-9373
  • Depositors only (login required):

Downloads

Downloads per month over past year