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Hierarchical classification of G-protein-coupled receptors with a PSO/ACO algorithm

Holden, Nicholas, Freitas, Alex A. (2006) Hierarchical classification of G-protein-coupled receptors with a PSO/ACO algorithm. In: Proceedings of the IEEE Swarm Intelligence Symposium (SIS '06). . pp. 77-84. IEEE Press (KAR id:14466)

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Abstract

In our previous work we have proposed a hybrid Particle

Swarm Optimisation / Ant Colony Optimisation (PSO/ACO)

algorithm for discovering classification rules. In this paper we

propose some modifications to the algorithm and apply it to a

challenging hierarchical classification problem. This is a

bioinformatics problem involving the prediction of G-Protein-

Coupled Receptor’s (GPCR) hierarchical functional classes. We

report the results of an extensive comparison between four

versions of swarm intelligence algorithms – two versions based

on our proposed algorithm and two versions based on Discrete

PSO for discovering classification rules proposed in the

literature. The experiments also compared the effectiveness of

different kinds of protein signatures when used as predictor

attributes, namely Prints, Interpro and Prosite signatures.

Item Type: Conference or workshop item (Paper)
Uncontrolled keywords: data mining, bioinformatics, classification, ant colony optimization, particle swarm optimization
Subjects: Q Science > QA Mathematics (inc Computing science) > QA 76 Software, computer programming,
Divisions: Divisions > Division of Computing, Engineering and Mathematical Sciences > School of Computing
Depositing User: Mark Wheadon
Date Deposited: 24 Nov 2008 18:04 UTC
Last Modified: 16 Nov 2021 09:52 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/14466 (The current URI for this page, for reference purposes)
Freitas, Alex A.: https://orcid.org/0000-0001-9825-4700
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