Concordance therapy: An intervention to help older people take antidepressants

Higgins, N. and Livingston, Gill and Katona, Cornelius (2004) Concordance therapy: An intervention to help older people take antidepressants. Journal of Affective Disorders, 81 (3). pp. 287-291. ISSN 0165-0327. (The full text of this publication is not available from this repository)

The full text of this publication is not available from this repository. (Contact us about this Publication)
Official URL


Background: Older people often do not adhere fully to antidepressant medication. Compliance Therapy improves adherence with antipsychotic medication. Objective: To adapt Compliance Therapy for use in older depressed patients, to pilot this 'Concordance Therapy' for feasibility and acceptability and to gain preliminary indications of its efficacy. Methods: Randomised controlled trial (RCT). Setting: Psychiatric services for older people in North London and Essex. Participants: A total of 19 older depressed patients. Intervention: 10 patients received Concordance Therapy over 3-4 sessions. Control: 9 patients received treatment as usual. Main outcome measure: medication adherence at 1 month. Secondary outcome measures: medication adherence at 3 months; depression severity, beliefs about medication, quality of life at 1 and 3 months; patient feedback about the therapy. Results: The therapy was acceptable to patients. Intervention patients were more likely to take antidepressants, had a higher quality of life, had less depressive symptomatology and were less likely to be cases of depression at 1 month. Beliefs around antidepressants at 1 month were more positive in the intervention group but this was not the case for medication in general. Limitations: As a pilot, patient numbers were small and the findings did not reach statistical significance. Three patients (1 intervention, 2 control) were in hospital and therefore offered medication at follow-up. Conclusion: Concordance Therapy for older people prescribed antidepressants is acceptable and feasible and shows sufficient promise of efficacy to justify an adequately powered RCT.

Item Type: Article
Uncontrolled keywords: older people depression antidepressants adherence concordance compliance
Subjects: R Medicine
Divisions: Faculties > Science Technology and Medical Studies > Kent Institute of Medicine and Health Sciences (KIMHS)
Depositing User: M.P. Stone
Date Deposited: 24 Sep 2008 16:05
Last Modified: 28 May 2014 07:47
Resource URI: (The current URI for this page, for reference purposes)
  • Depositors only (login required):