Khan, Adan and Siddiqui, Momina Riaz and Davidson, Leezza Faboro and Yip, Benjamin and Chelikani, Lisa and Faraz, Fatima and Courtnage, Lewis and Sadiq, Soban (2025) Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease. In: Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases. CRC Press, pp. 92-111. E-ISBN 978-1-003-48162-1. (doi:10.1201/9781003481621-6) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:113595)
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Language: English Restricted to Repository staff only until 23 June 2026. 
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| Official URL: https://doi.org/10.1201/9781003481621-6 |
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Abstract
Cerebral small vessel disease (CSVD) is a significant contributor to cognitive decline, stroke, and dementia. This chapter explores the role of biomarkers in CSVD, examining their potential in diagnosis, prognosis, and disease monitoring. We discuss various biomarkers related to endothelial dysfunction, inflammation, and neuroimaging features. The chapter highlights the clinical implications of these biomarkers, current challenges in their application, and future directions in CSVD biomarker research. Emerging technologies, multi-marker approaches, and the potential for personalized medicine are considered. While significant progress has been made, further research is needed to fully realize the potential of biomarkers in improving CSVD management and patient outcomes.
| Item Type: | Book section |
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| DOI/Identification number: | 10.1201/9781003481621-6 |
| Subjects: | R Medicine |
| Institutional Unit: | Schools > Kent and Medway Medical School |
| Former Institutional Unit: |
There are no former institutional units.
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| Funders: | University of Kent (https://ror.org/00xkeyj56) |
| Depositing User: | Soban Sadiq |
| Date Deposited: | 27 Mar 2026 23:07 UTC |
| Last Modified: | 01 Apr 2026 13:14 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/113595 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Sadiq, Soban.
| Creator's ORCID: |
 https://orcid.org/0009-0008-9016-1807
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