Role of Plasma Inflammatory and Blood Biomarkers in Cerebral Small Vessel Disease

Cerebral small vessel disease (CSVD) is a significant contributor to cognitive decline, stroke, and dementia. This chapter explores the role of biomarkers in CSVD, examining their potential in diagnosis, prognosis, and disease monitoring. We discuss various biomarkers related to endothelial dysfunction, inflammation, and neuroimaging features. The chapter highlights the clinical implications of these biomarkers, current challenges in their application, and future directions in CSVD biomarker research. Emerging technologies, multi-marker approaches, and the potential for personalized medicine are considered. While significant progress has been made, further research is needed to fully realize the potential of biomarkers in improving CSVD management and patient outcomes.