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Enhancement of dissolution rate of piroxicam using liquisolid compacts

Javadzadeh, Yousef, Siahi, Mohammad Reza, Barzegar-Jalali, Mohammad, Nokhodchi, Ali (2005) Enhancement of dissolution rate of piroxicam using liquisolid compacts. IL Farmaco, 60 . pp. 361-365. ISSN 0014-827X. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:11300)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)

Abstract

Piroxicam is a poorly soluble, highly permeable drug and the rate of its oral absorption is often controlled by the dissolution rate in the gastrointestinal. The poor dissolution rate of water-insoluble drugs is still a major problem confronting the pharmaceutical industry. There are

(coating powder material) was kept constant in all formulations. The results showed that liquisolid compacts demonstrated significantly higher drug release rates than those of conventionally made (capsules and directly compressed tablets containing micronized piroxicam). This

was due to an increase in wetting properties and surface of drug available for dissolution.

Item Type: Article
Subjects: Q Science
Divisions: Faculties > Sciences > Medway School of Pharmacy
Depositing User: Ali Nokhodchi
Date Deposited: 09 Sep 2008 15:15 UTC
Last Modified: 28 May 2019 13:48 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/11300 (The current URI for this page, for reference purposes)
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