5-Amino-6-Hydroxy-3,4,5,6-Tetrahydropyran-2-One (Hat) - a Stable, Cyclic Form of Glutamate 1-Semialdehyde, the Natural Precursor for Tetrapyrroles

Jordan, P.M. and Cheung, K.M. and Sharma, R.P. and Warren, Martin J. (1993) 5-Amino-6-Hydroxy-3,4,5,6-Tetrahydropyran-2-One (Hat) - a Stable, Cyclic Form of Glutamate 1-Semialdehyde, the Natural Precursor for Tetrapyrroles. Tetrahedron Letters, 34 (7). pp. 1177-1180. ISSN 0040-4039 . (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1016/S0040-4039(00)77521-6

Abstract

Glutamate 1-semialdehyde is shown to exist in a cyclic form, 5-amino-6-hydroxy-3,4,5,6-tetrahydropyran-2-one (HAT), which explains its unexpectedly high stability for an alpha-aminoaldehyde. It is proposed that the cyclic form is the actual intermediate in the biosynthesis of tetrapyrroles.

Item Type: Article
Uncontrolled keywords: delta-aminolevulinate greening barley biosynthesis
Subjects: Q Science
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences
Depositing User: Martin Warren
Date Deposited: 21 Oct 2009 08:26
Last Modified: 04 Jun 2014 13:58
Resource URI: https://kar.kent.ac.uk/id/eprint/11112 (The current URI for this page, for reference purposes)
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