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Theoretical modeling of oral absorption of barbiturates

Ghafourian, Taravat, Barzegar-Jalali, Mohammad (2002) Theoretical modeling of oral absorption of barbiturates. IL Farmaco, 57 (7). pp. 565-567. ISSN 0014-827X. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:10763)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.

Abstract

The structural characteristics governing gastric absorption of barbiturates were studied using QSAR methodology. The results

showed that the gastric absorption rate constant could be modeled using the theoretical parameters, accessible surface area,

atomic charges and electrostatic potentials. Using molecular connectivity indexes was also satisfactory in modeling the absorption.

© 2002 E´ ditions scientifiques et me´dicales Elsevier SAS.

Item Type: Article
Uncontrolled keywords: absorption; QSAR; barbiturate; gastric; oral absorption
Subjects: Q Science
Q Science > QD Chemistry
Divisions: Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Taravat Ghafourian
Date Deposited: 17 Sep 2008 16:58 UTC
Last Modified: 16 Nov 2021 09:49 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/10763 (The current URI for this page, for reference purposes)

University of Kent Author Information

Ghafourian, Taravat.

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