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Pharmacogenetic testing in psychiatry: Perspective on clinical utility

Adiukwu, Frances, Adesokun, Olufisayo, Essien, Emmanuel, Yalcin, Nadir, Ransing, Ramdas, Nagendrappa, Sachin, Jatchavala, Chonnakarn, Olakunke, Ayotunde Bolatito, Nawaz, Faisal A., Khan, Nagina and others. (2023) Pharmacogenetic testing in psychiatry: Perspective on clinical utility. Asian Journal of Psychiatry, 86 . Article Number 103674. ISSN 1876-2026. (doi:10.1016/j.ajp.2023.103674) (KAR id:103808)

Abstract

Pharmacogenetic studies the influence of inherited characteristics on medication. While different from pharmacogenomics, which is a study of the entire genome in relation to medication effect, their distinction remains inconsistent, and the two terms are used interchangeably. Although the potential of pharmacogenomics in psychiatry is apparent and its clinical utility is suboptimal, the uptake of recommendations and guidelines is minimal and research into PGx is not diverse. This article offers an overview of pharmacogenetics (PGx) in psychiatry, explores the difficulties, and provides recommendations on improving its applicability and clinical utility.

Item Type: Article
DOI/Identification number: 10.1016/j.ajp.2023.103674
Uncontrolled keywords: Pharmacogenomics,Precision medicine,Psychiatry PGx
Subjects: H Social Sciences
Q Science
R Medicine
Divisions: Divisions > Division for the Study of Law, Society and Social Justice > School of Social Policy, Sociology and Social Research > Centre for Health Services Studies
Funders: University of Oxford (https://ror.org/052gg0110)
Depositing User: Nagina Khan
Date Deposited: 15 Nov 2023 12:24 UTC
Last Modified: 10 Jan 2024 06:28 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/103808 (The current URI for this page, for reference purposes)

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