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Dysglycemia and arrhythmias.

Sun, Dong-Kun, Zhang, Nan, Liu, Ying, Qiu, Jiu-Chun, Tse, Gary, Li, Guang-Ping, Roever, Leonardo, Liu, Tong (2023) Dysglycemia and arrhythmias. World journal of diabetes, 14 (8). pp. 1163-1177. ISSN 1948-9358. (doi:10.4239/wjd.v14.i8.1163) (KAR id:102798)


Disorders in glucose metabolism can be divided into three separate but interrelated domains, namely hyperglycemia, hypoglycemia, and glycemic variability. Intensive glycemic control in patients with diabetes might increase the risk of hypoglycemic incidents and glucose fluctuations. These three dysglycemic states occur not only amongst patients with diabetes, but are frequently present in other clinical settings, such as during critically ill. A growing body of evidence has focused on the relationships between these dysglycemic domains with cardiac arrhythmias, including supraventricular arrhythmias (primarily atrial fibrillation), ventricular arrhythmias (malignant ventricular arrhythmias and QT interval prolongation), and bradyarrhythmias (bradycardia and heart block). Different mechanisms by which these dysglycemic states might provoke cardiac arr-hythmias have been identified in experimental studies. A customized glycemic control strategy to minimize the risk of hyperglycemia, hypoglycemia and glucose variability is of the utmost importance in order to mitigate the risk of cardiac arrhythmias. [Abstract copyright: ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.]

Item Type: Article
DOI/Identification number: 10.4239/wjd.v14.i8.1163
Uncontrolled keywords: Hypoglycemia, Hyperglycemia, Glucose variability, Dysglycemia, Cardiac arrhythmia
Subjects: R Medicine
Divisions: Divisions > Division of Natural Sciences > Kent and Medway Medical School
Funders: National Natural Science Foundation of China (
SWORD Depositor: JISC Publications Router
Depositing User: JISC Publications Router
Date Deposited: 11 Oct 2023 15:23 UTC
Last Modified: 11 Oct 2023 15:23 UTC
Resource URI: (The current URI for this page, for reference purposes)

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