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Process parameter optimisation for manufacturing porous bioactive silicate glass microspheres via flame spheroidisation: The goldilocks effect

Islam, Md Towhidul, Parsons, Andrew J, Nuzulia, Nur Aisyah, Sari, Yessie W., Ren, Hong, Booth, Jonathan, Ahmed, Ifty (2023) Process parameter optimisation for manufacturing porous bioactive silicate glass microspheres via flame spheroidisation: The goldilocks effect. Journal of Non-Crystalline Solids, 614 . Article Number 122393. ISSN 0022-3093. (doi:10.1016/j.jnoncrysol.2023.122393) (KAR id:101437)

Abstract

This study investigated the influence of flame spheroidisation process parameters for successfully manufacturing solid (dense) and highly porous microspheres from Food and Drug Administration approved bioactive 45S5 glass and 45S5 with addition of viscosity modifiers (i.e. 2 and 5 mol% borax and V2O5), compared against successfully processed phosphate glass microspheres (termed P40). Characterisation studies performed included thermal analysis (SDT), glass viscosity measurements using high temperature rotational viscometry and hot stage microscopy, X-ray diffraction, scanning electron microscopy and energy dispersive X-ray analysis. This study revealed that aside from intrinsic material properties (i.e. melt temperature and viscosity profiles), process parameters including starting glass particle size, cooling rate and gas flow rates were important factors in achieving the desired porous glass microsphere morphology. Considering the above influential factors, a processing model has been proposed for the manufacture of highly porous microspheres from bioactive silicate glasses.

Item Type: Article
DOI/Identification number: 10.1016/j.jnoncrysol.2023.122393
Additional information: For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission.
Uncontrolled keywords: Bioactive glasses; Porous microspheres; Viscosity; Thermal properties; Flame spheroidisation
Subjects: Q Science
Q Science > QC Physics
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Funders: Engineering and Physical Sciences Research Council (https://ror.org/0439y7842)
British Council (https://ror.org/00t3pr326)
SWORD Depositor: JISC Publications Router
Depositing User: JISC Publications Router
Date Deposited: 09 Jun 2023 14:24 UTC
Last Modified: 27 Feb 2024 10:54 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/101437 (The current URI for this page, for reference purposes)

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