Hansen, Jacob A., Sumbayev, Vadim V., Gothelf, Kurt V. (2007) An electrochemical sensor based on the human estrogen receptor ligand binding domain. NANO Letters, 7 (9). pp. 2831-2834. ISSN 1530-6984. (doi:10.1021/nl071451l) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:10056)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: http://dx.doi.org/10.1021/nl071451l |
Abstract
Three different conformations of the ligand binding domain of the human estrogen receptor (ER-LBD) are observed for the native state when binding an agonist and when binding an antagonist. By conjugating ER-LBD conformation specific peptides to CdS nanoparticles, the three different states can be identified by anodic stripping voltarnmetry. This electrochemical sensor can detect and distinguish the binding of different ligands to the human estrogen receptor.
| Item Type: | Article |
|---|---|
| DOI/Identification number: | 10.1021/nl071451l |
| Subjects: | Q Science |
| Divisions: | Divisions > Division of Natural Sciences > Medway School of Pharmacy |
| Depositing User: | Vadim Sumbayev |
| Date Deposited: | 18 Jul 2008 14:08 UTC |
| Last Modified: | 16 Nov 2021 09:48 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/10056 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Sumbayev, Vadim V..
| Creator's ORCID: |
 https://orcid.org/0000-0002-9404-5626
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|---|---|
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