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Number of items: 54.
Article
| Cunningham, K.P. and Holden, R.G. and Escribano-Subias, P. and Cogolludo, A. and Veale, Emma L. and Mathie, Alistair (2018) Characterisation and regulation of wild type and mutant TASK-1 two pore domain potassium channels indicated in pulmonary arterial hypertension. The Journal of Physiology, . ISSN 0022-3751. E-ISSN 1469-7793. (doi:https://doi.org/10.1113/JP277275) (Full text available) |
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| Mondejar-Parreño, Gema and Morales-Cano, Daniel and Barreira, Bianca and Callejo, Maria and Ruiz-Cabello, Jesus and Moreno, Laura and Esquivel-Ruiz, Sergio and Mathie, Alistair and Butrous, Ghazwan S. and Perez-Vizcaino, Francisco and Cogolludo, Angel (2018) HIV transgene expression impairs K+ channel function in the pulmonary vasculature. American Journal of Physiology - Lung Cellular and Molecular Physiology, 315 (5). L711-L723. ISSN 1040-0605. (doi:https://doi.org/10.1152/ajplung.00045.2018) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) |
![[img]](https://kar.kent.ac.uk/style/images/fileicons/application_pdf.png)
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| Fernández-Fernández, Diego and Cadaveira-Mosquera, Alba and Rueda-Ruzafa, Lola and Herrera-Pérez, Salvador and Veale, Emma L. and Reboreda, Antonio and Mathie, Alistair and Lamas, J Antonio (2018) Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons. PloS ONE, 13 (6). e0199282. ISSN 1932-6203. (doi:https://doi.org/10.1371/journal.pone.0199282) (Full text available) |
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| Veale, Emma L. and Stewart, Adrian J. and Mathie, Alistair and Lall, Satvinder K. and Rees-Roberts, Melanie and Savickas, Vilius and Bhamra, Sukvinder K. and Corlett, Sarah (2018) Pharmacists detecting atrial fibrillation (PDAF) in primary care during the influenza vaccination season: a multisite, cross-sectional screening protocol. BMJ Open, 8 (3). e021121. ISSN 2044-6055. (doi:https://doi.org/10.1136/bmjopen-2017-021121) (Full text available) |
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| Loucif, Alexandre J C and Saintot, Pierre-Philippe and Liu, Jia and Antonio, Brett M and Zellmer, Shannon G and Yoger, Katrina and Veale, Emma L. and Wilbrey, Anna and Omoto, Kiyoyuki and Cao, Lishuang and Gutteridge, Alex and Castle, Neil A and Stevens, Edward B and Mathie, Alistair (2017) GI-530159, a novel, selective, mechano-sensitive K2P channel opener, reduces rat dorsal root ganglion (DRG) neuron excitability. British Journal of Pharmacology, 175 (12). pp. 2272-2283. ISSN 0007-1188. E-ISSN 1476-5381. (doi:https://doi.org/10.1111/bph.14098) (Full text available) |
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| Olschewski, Andrea and Veale, Emma L. and Nagy, Bence M. and Nagaraj, Chandran and Kwapiszewska, Grazyna and Antigny, Fabrice and Lambert, Mélanie and Humbert, Marc and Czirják, Gábor and Enyedi, Péter and Mathie, Alistair (2017) TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications. European Respiratory Journal, 50 (5). ISSN 0903-1936. E-ISSN 1399-3003. (doi:https://doi.org/10.1183/13993003.00754-2017) (Full text available) |
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| Wright, Paul D. and Veale, Emma L. and McCoull, David and Tickle, David C. and Large, Jonathan M. and Ococks, Emma and Gothard, Gemma and Kettleborough, Catherine and Mathie, Alistair and Jerman, Jeffrey (2017) Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3. Biochemical and Biophysical Research Communications, 493 (1). pp. 444-450. ISSN 0006-291X. E-ISSN 1090-2104. (doi:https://doi.org/10.1016/j.bbrc.2017.09.002) (Full text available) |
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| Ali, Zahara and Kosanovic, Djuro and Kolosionek, Ewa and Schermuly, Ralph T and Graham, Brian B and Mathie, Alistair and Butrous, Ghazwan S. (2017) Enhanced inflammatory cell profiles in schistosomiasis-induced pulmonary vascular remodeling. Pulmonary circulation, 7 (1). pp. 244-252. ISSN 2045-8932. E-ISSN 2045-8940. (doi:https://doi.org/10.1086/690687) (Full text available) |
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| Veale, Emma L. and Mathie, Alistair (2016) Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels. British Journal of Pharmacology, 173 (10). pp. 1639-1652. ISSN 0007-1188. E-ISSN 1476-5381. (doi:https://doi.org/10.1111/bph.13465) (Full text available) |
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| Mathie, Alistair and Veale, Emma L. (2014) Two-pore domain potassium channels: potential therapeutic targets for the treatment of pain. Pflügers Archiv : European journal of physiology, 467 (5). pp. 931-43. ISSN 0031-6768. E-ISSN 1432-2013. (doi:https://doi.org/10.1007/s00424-014-1655-3) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Veale, Emma L. and Al-Moubarak, Ehab and Bajaria, Naina and Omoto, Kiyoyuki and Cao, Lishuang and Tucker, Stephen J and Stevens, Edward B and Mathie, Alistair (2014) Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels. Molecular pharmacology, 85 (5). pp. 671-81. ISSN 1521-0111. (doi:https://doi.org/10.1124/mol.113.091199) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| El Hachmane, Mickael F. and Rees, Kathryn A. and Veale, Emma L. and Sumbayev, Vadim V. and Mathie, Alistair (2014) Enhancement of TWIK-related Acid-sensitive Potassium Channel 3 (TASK3) Two-pore Domain Potassium Channel Activity by Tumor Necrosis Factor. Journal of Biological Chemistry, 289 (3). pp. 1388-1401. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.M113.500033) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Veale, Emma L. and Al-Moubarak, Ehab and Bajaria, Naina and Omoto, Koypyuki and Cao, Lishunag and Tucker, Stephen J. and Stevens, Edward B. and Mathie, Alistair (2014) Influence of the N-terminus on the Biophysical Properties and Pharmacology of TREK1 Potassium Channels. Molecular Pharmacology, 85 (5). pp. 671-681. ISSN 0026-895X. E-ISSN 1521-0111. (doi:https://doi.org/10.1124/mol.113.091199) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Veale, Emma L. and Hassan, Mustafa and Walsh, Yvonne and Al-Moubarak, Ehab and Mathie, Alistair (2014) Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome. Molecular Pharmacology, 85 (3). pp. 397-407. ISSN 1521-0111. (doi:https://doi.org/10.1124/mol.113.090530) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Benson, Helen E and Davenport, Anthony P and Mathie, Alistair and McGrath, Ian J C and Pawson, Adam J and Peters, John A. and Sharman, Joanna L and Spedding, Michael and Harmar, Anthony J (2012) GuideToPharmacology.org--an update. British Journal of Pharmacology, 167 (4). pp. 697-8. ISSN 0007-1188. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2011) Guide to Receptors and Channels (GRAC), 5th edition. British Journal of Pharmacology, 164 (s1). S1-s2. ISSN 0007-1188. (doi:https://doi.org/10.1111/j.1476-5381.2011.01649_1.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Rees, Kathryn A and El Hachmane, Mickael F. and Veale, Emma L. (2010) Trafficking of neuronal two pore domain potassium channels. Current Neuropharmacology, 8 (3). pp. 276-286. ISSN 1570-159X. (doi:https://doi.org/10.2174/157015910792246146) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Veale, Emma L. and Rees, Kathryn A. and Mathie, Alistair and Trapp, Stefan (2010) Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain. The Journal of biological chemistry, 285 (38). pp. 29295-304. ISSN 1083-351X. (doi:https://doi.org/10.1074/jbc.M110.108423) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Al-Moubarak, Ehab and Veale, Emma L. (2010) Gating of two pore domain potassium channels. Journal of Physiology, 588 . pp. 3149-56. ISSN 0022-3751. (doi:https://doi.org/10.1113/jphysiol.2010.192344) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair (2010) Ion channels as novel therapeutic targets in the treatment of pain. Journal of Pharmacy and Pharmacology, 62 (9). pp. 1089-95. ISSN 0022-3573. (doi:https://doi.org/10.1111/j.2042-7158.2010.01131.x.) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Rees, Kathryn A. and El Hachmane, Mickael F. and Veale, Emma L. (2010) Trafficking of neuronal two pore domain potassium channels. Current Neuropharmacology, 8 (3). pp. 276-86. ISSN 1875-6190. (doi:https://doi.org/10.2174/157015910792246146) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2009) Guide to Receptors and Channels (GRAC), 4th edition. British Journal of Pharmacology, 158 . S1-S1. ISSN 0007-1188. (doi:https://doi.org/10.1111/j.1476-5381.2009.00499.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Clarke, Catherine E. and Veale, Emma L. and Wyse, Ken and Vandenberg, Jamie I. and Mathie, Alistair (2008) The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function. Journal of Biological Chemistry, 283 (25). pp. 16985-16992. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.M801368200) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2008) Guide to Receptors and Channels (GRAC), 3rd edition. British Journal of Pharmacology, 153 (supple). S1-S209. ISSN 0007-1188. (doi:https://doi.org/10.1038/sj.bjp.0707746) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Veale, Emma L. and Buswell, R. and Clarke, Catherine E. and Mathie, Alistair (2007) Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide. British Journal of Pharmacology, 152 (5). pp. 778-786. ISSN 0007-1188. (doi:https://doi.org/10.1038/sj.bjp.0707436) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Brickley, Stephen G. and Aller, M. Isabel and Sandu, Cristina and Veale, Emma L. and Alder, Felicity G. and Sambi, Harvinder and Mathie, Alistair and Wisden, William (2007) TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. Journal of Neuroscience, 27 (35). pp. 9329-9340. ISSN 0270-6474. (doi:https://doi.org/10.1523/JNEUROSCI.1427-07.2007) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Veale, Emma L. (2007) Therapeutic potential of neuronal two-pore domain potassium-channel modulators. Current Opinion in Investigational Drugs, 8 (7). pp. 555-562. ISSN 1472-4472. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Veale, Emma L. and Kennard, Louise E. and Sutton, Gemma L. and MacKenzie, Georgina and Sandu, Cristina and Mathie, Alistair (2007) G(alpha)q-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C. Molecular Pharmacology, 71 (6). pp. 1666-1675. ISSN 0026-895X. (doi:https://doi.org/10.1124/mol.106.033241) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2007) Guide to Receptors and Channels, 2nd edition (2007 Revision). British Journal of Pharmacology, 150 (Supple). S1-S1. ISSN 0007-1188. (doi:https://doi.org/10.1038/sj.bjp.0707199) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair (2007) Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors. Journal of Physiology, 578 (2). pp. 377-385. ISSN 0022-3751. (doi:https://doi.org/10.1113/jphysiol.2006.121582) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Linden, Anni-Maija and Aller, M. Isabel and Leppa, Elli and Vekovischeva, Olga and Aitta-Aho, Teemu and Veale, Emma L. and Mathie, Alistair and Rosenberg, Per and Wisden, William and Korpi, Esa R. (2006) The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists. Journal of Pharmacology and Experimental Therapeutics, 317 (2). pp. 615-626. ISSN 0022-3565. (doi:https://doi.org/10.1124/jpet.105.098525) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2006) Guide to receptors and channels, 2nd edition. British Journal of Pharmacology, 147 (Supple). S1-168. ISSN 0007-1188. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Sutton, Gemma L. and Clarke, Catherine E. and Veale, Emma L. (2006) Zinc and copper: pharmacological probes and endogenous modulators of neuronal excitability. Pharmacology & Therapeutics, 111 (3). pp. 567-583. ISSN 0163-7258. (doi:https://doi.org/10.1016/j.pharmthera.2005.11.004) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Aller, M. Isabel and Veale, Emma L. and Linden, Anni-Maija and Sandu, Cristina and Schwaninger, Markus and Evans, Louisa J. and Korpi, Esa R. and Mathie, Alistair and Wisden, William and Brickley, Stephen G. (2005) Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons. Journal of Neuroscience, 25 (49). pp. 11455-11467. ISSN 0270-6474. (doi:https://doi.org/10.1523/JNEUROSCI.3153-05.2005) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2005) Guide to receptors and channels, 1st edition (2005 revision). British Journal of Pharmacology, 144 (Supple). S1-S128. ISSN 0007-1188. (doi:https://doi.org/10.1038/sj.bjp.0706158) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Kennard, Louise E. and Chumbley, Justin R. and Ranatunga, Kishani M. and Armstrong, Stephanie J. and Veale, Emma L. and Mathie, Alistair (2005) Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine. British Journal of Pharmacology, 144 (6). pp. 821-829. ISSN 0007-1188. (doi:https://doi.org/10.1038/sj.bjp.0706068) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Alexander, Stephen and Mathie, Alistair and Peters, John A. (2004) Guide to receptors and channels, 1st edition. British Journal of Pharmacology, 141 (supple). S1-S126. ISSN 0007-1188. (doi:https://doi.org/10.1038/sj.bjp.0705672) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Clarke, Catherine E. and Veale, Emma L. and Green, Paula J. and Meadows, Helen J. and Mathie, Alistair (2004) Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc. Journal of Physiology, 560 (1). pp. 51-62. ISSN 0022-3751. (doi:https://doi.org/10.1113/jphysiol.2004.070292) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Gruss, Marco and Bushell, Trevor J. and Bright, D.P. and Lieb, William R. and Mathie, Alistair and Franks, Nicholas P. (2004) Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane. Molecular Pharmacology, 65 (2). pp. 443-452. ISSN 0026-895X. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Gruss, Marco and Mathie, Alistair and Lieb, William R. and Franks, Nicholas P. (2004) The two-pore-domain K(+) channels TREK-1 and TASK-3 are differentially modulated by copper and zinc. Molecular Pharmacology, 66 (3). pp. 530-537. ISSN 0026-895X. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Kennard, Louise E. and Veale, Emma L. (2003) Neuronal ion channels and their sensitivity to extremely low frequency weak electric field effects. Radiation Protection Dosimetry, 106 (4). pp. 311-316. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Clarke, Catherine E. and Ranatunga, Kishani M. and Veale, Emma L. (2003) What are the roles of the many different types of potassium channel expressed in cerebellar granule cells? Cerebellum, 2 (1). pp. 11-25. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Mathie, Alistair and Clarke, Catherine E. (2002) Background potassium channels move into focus. Journal of Physiology, 542 (2). p. 334. ISSN 0022-3751. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Boyd, David F. and Mathie, Alistair (2002) Inhibition of the potassium current IK(SO), in cerebellar granule cells, by the inhibitors of MEK1 activation, PD 98059 and U 0126. Neuropharmacology, 42 (2). pp. 221-228. (doi:https://doi.org/10.1016/S0028-3908(01)00168-X) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Bushell, Trevor J. and Clarke, Catherine E. and Mathie, Alistair and Robertson, Brian (2002) Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones. British Journal of Pharmacology, 135 (3). pp. 705-712. ISSN 0007-1188. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Boyd, David F. and Millar, Julie A. and Watkins, Christopher S. and Mathie, Alistair (2000) The role of Ca2+ stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells. Journal of Physiology, 529 Pt (1). pp. 321-331. ISSN 0022-3751. (doi:https://doi.org/10.1111/j.1469-7793.2000.00321.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Prothero, L S and Mathie, Alistair and Richards, C D (2000) Purinergic and muscarinic receptor activation activates a common calcium entry pathway in rat neocortical neurons and glial cells. Neuropharmacology, 39 (10). pp. 1768-78. ISSN 0028-3908. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Millar, Julie A. and Barratt, Lynne and Southan, Andrew P. and Page, Karen M. and Fyffe, Robert E. and Robertson, Brian and Mathie, Alistair (2000) A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons. Proceedings of the National Academy of Sciences of the United States of America, 97 (7). pp. 3614-8. ISSN 0027-8424. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
| Jones, Glyn and Boyd, David F. and Yeung, Shuk Yin and Mathie, Alistair (2000) Inhibition of delayed rectifier K+ conductance in cultured rat cerebellar granule neurons by activation of calcium-permeable AMPA receptors. European Journal of Neuroscience, 12 (3). pp. 935-944. ISSN 0953-816X. (doi:https://doi.org/10.1046/j.1460-9568.2000.00983.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
Book section
| Mathie, Alistair and Veale, Emma L. (2008) Neuronal Potassium Channels. In: Binder, Marc and Hirokawa, Nobutaka and Windhorst, Uwe, eds. Encyclopedia of Neuroscience (5 volumes). Springer Verlag, Berlin, pp. 2792-2797. ISBN 978-3-540-23735-8. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) |
Thesis
| Cunningham, Kevin Peter (2018) Functional Properties and Pharmacological Regulation of Two-Pore Domain Potassium Channels Associated with Pulmonary Disorders. Doctor of Philosophy (PhD) thesis, University of Kent,. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) |
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| Lee, Mun Ching (2018) Regulation of Voltage-gated Potassium (Kv) and Two-Pore Domain Potassium (K2P) Channels implicated in Pulmonary Hypertension. Doctor of Philosophy (PhD) thesis, University of Kent,. (Full text available) |
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| Walsh, Yvonne (2017) PHARMACOLOGICAL REGULATION OF TREK1, TREK2 AND TRESK TWO PORE DOMAIN POTASSIUM CHANNELS. Doctor of Philosophy (PhD) thesis, University of Kent,. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) |
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| Atkinson, Lynsey A (2014) The Role of TASK-3 Two-Pore Domain Potassium Channels in the Entrainment of Mammalian Circadian Rhythms. Doctor of Philosophy (PhD) thesis, University of Kent,. (Full text available) |
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