Browse by Person (creator, editor, contributor, etc.)
 | Up a level |
Jump to: Article
Number of items: 1.
Article
| Osborne, James D. and Matthews, Thomas P. and McHardy, Tatiana and Proisy, Nicolas and Cheung, Kwai-Ming J. and Lainchbury, Michael and Brown, Nathan and Walton, Michael I. and Eve, Paul D. and Boxall, Katherine J. and Hayes, Angela and Henley, Alan T. and Valenti, Melanie R. and De Haven Brandon, Alexis K. and Box, Gary and Jamin, Yann and Robinson, Simon P. and Westwood, Isaac M. and van Montfort, Rob L. M. and Leonard, Philip M. and Lamers, Marieke B. A. C. and Reader, John C. and Aherne, G. Wynne and Raynaud, Florence I. and Eccles, Suzanne A. and Garrett, Michelle D. and Collins, Ian (2016) Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). Journal of Medicinal Chemistry, 59 (11). pp. 5221-5237. ISSN 0022-2623. (doi:https://doi.org/10.1021/acs.jmedchem.5b01938) (Full text available) |
|
