Skip to main content
Kent Academic Repository

Browse by Person (creator, editor, contributor, etc.)

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Item Type | Date | No Grouping
Number of items: 38.

Article

Inchingolo, Alessio Vincenzo and Previs, Samantha Beck and Previs, Michael J. and Warshaw, David M. and Kad, Neil M (2019) Revealing the mechanism of how cardiac myosin-binding protein C N-terminal fragments sensitize thin filaments for myosin binding. Proceedings of the National Academy of Sciences, . ISSN 0027-8424. (doi:https://doi.org/10.1073/pnas.1816480116) (Full text available)
[img]
Preview

Barnett, Jamie T. and Kad, Neil M (2018) Understanding the coupling between DNA damage detection and UvrA’s ATPase using bulk and single molecule kinetics. The FASEB Journal, . ISSN 0892-6638. (doi:https://doi.org/10.1096/fj.201800899R) (Full text available)
[img]
Preview

Van Houten, Bennett and Kad, Neil M (2018) Single-cell mutagenic responses and cell death revealed in real time. Proceedings of the National Academy of Sciences of the United States of America, 115 (28). pp. 7168-7170. ISSN 0027-8424. (doi:https://doi.org/10.1073/pnas.1808986115) (Full text available)
[img]
Preview

Springall, Luke and Hughes, Craig D. and Simons, Michelle and Azinas, Stavros and Van Houten, Bennett and Kad, Neil M (2018) Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival. Nucleic Acids Research, 46 (3). pp. 1256-1265. ISSN 0305-1048. E-ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkx1244) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
[img]
Preview
[img]

Kad, Neil M and Van Houten, Bennett (2016) DNA repair: Clamping down on copy errors. Nature, . ISSN 0028-0836. (doi:https://doi.org/10.1038/nature20475) (Full text available)
[img]
Preview

Kong, Muwen and Liu, Lili and Chen, Xuejing and Driscoll, Katherine I. and Mao, Peng and Böhm, Stefanie and Kad, Neil M and Watkins, Simon C. and Bernstein, Kara A. and Wyrick, John J. and Min, Jung-Hyun and Van Houten, Bennett (2016) Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition Process. Molecular Cell, 64 (2). pp. 376-387. ISSN 1097-2765. (doi:https://doi.org/10.1016/j.molcel.2016.09.005) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
[img]

Lin, Jiangguo and Countryman, Preston and Chen, Haijiang and Pan, Hai and Fan, Yanlin and Jiang, Yunyun and Kaur, Parminder and Miao, Wang and Gurgel, Gisele and You, Changjiang and Piehler, Jacob and Kad, Neil M and Riehn, Robert and Opresko, Patricia L and Smith, Susan and Tao, Yizhi Jane and Wang, Hong (2016) Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing. Nucleic acids research, . ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkw518) (Full text available)
[img]
Preview

Simons, Michelle and Pollard, Mark R and Hughes, Craig D and Ward, Andrew D and Van Houten, Bennett and Towrie, Mike and Botchway, Stan W and Parker, Anthony W and Kad, Neil M (2015) Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optically trapped nanoprobe. Scientific reports, 5 . p. 18486. ISSN 2045-2322. (doi:https://doi.org/10.1038/srep18486) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Walcott, Sam and Kad, Neil M (2015) Direct Measurements of Local Coupling between Myosin Molecules Are Consistent with a Model of Muscle Activation. PLoS computational biology, 11 (11). ISSN 1553-7358. (doi:https://doi.org/10.1371/journal.pcbi.1004599) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Cheruvara, Harish and Kad, Neil M and Mason, Jody M (2015) Intracellular Screening of a Peptide Library to Derive a Potent Peptide Inhibitor of ?-Synuclein Aggregation. Journal of Biological Chemistry, 290 (12). pp. 7426-7435. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.M114.620484) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Desai, R. A. and Geeves, M. A. and Kad, Neil M (2015) Using Fluorescent Myosin to Directly Visualize Cooperative Activation of Thin Filaments. Journal of Biological Chemistry, . jbc.M114.609743-jbc.M114.609743. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.M114.609743) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Acerra, Nicola and Kad, Neil M and Cheruvara, Harish and Mason, Jody M (2014) Intracellular selection of peptide inhibitors that target disulphide-bridged A?42 oligomers. Protein science : a publication of the Protein Society, 23 (9). pp. 1262-1274. E-ISSN 1469-896X. (doi:https://doi.org/10.1002/pro.2509) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Van Houten, Bennett and Kad, Neil M (2014) Investigation of bacterial nucleotide excision repair using single-molecule techniques. DNA repair, 20 . pp. 41-48. ISSN 1568-7856. (doi:https://doi.org/10.1016/j.dnarep.2013.10.012) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Van Houten, Bennett (2014) Single molecule approaches: watching DNA repair one molecule at a time: Preface. DNA repair, 20 . p. 1. ISSN 1568-7856. (doi:https://doi.org/10.1016/j.dnarep.2014.06.007) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hughes, Craig D and Simons, Michelle and Mackenzie, Cassidy E and Van Houten, Bennett and Kad, Neil M (2014) Single molecule techniques in DNA repair:a primer. DNA repair, 20 . pp. 2-13. ISSN 1568-7856. (doi:https://doi.org/10.1016/j.dnarep.2014.02.003) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Acerra, Nicola and Kad, Neil M and Griffith, Douglas A and Ott, Stanislav and Crowther, Damian C and Mason, Jody M (2014) Retro-inversal of intracellular selected ?-amyloid-interacting peptides: implications for a novel Alzheimer's disease treatment. Biochemistry, 53 (13). pp. 2101-2111. ISSN 1520-4995. (doi:https://doi.org/10.1021/bi5001257) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Lin, Jiangguo and Countryman, Preston and Buncher, Noah and Kaur, Parminder and Longjiang, E. and Zhang, Yiyun and Gibson, Greg and You, Changjiang and Watkins, Simon C and Piehler, Jacob and Opresko, Patricia L and Kad, Neil M and Wang, Hong (2014) TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres. Nucleic acids research, 42 (4). pp. 2493-2504. ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkt1132) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Acerra, Nicola and Kad, Neil M and Mason, Jody M (2013) Combining intracellular selection with protein-fragment complementation to derive A? interacting peptides. Protein engineering, design & selection : PEDS, 26 (7). pp. 463-470. ISSN 1741-0126. E-ISSN 1741-0134. (doi:https://doi.org/10.1093/protein/gzt021) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hughes, Craig D and Wang, Hong and Ghodke, Harshad and Simons, Michelle and Towheed, Atif and Peng, Ye and Van Houten, Bennett and Kad, Neil M (2013) Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes. Nucleic acids research, 41 (9). pp. 4901-4912. ISSN 0305-1048. E-ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkt177) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Zhang, Chong and Ali, M Yusuf and Warshaw, David M and Kad, Neil M (2012) A branched kinetic scheme describes the mechanochemical coupling of Myosin Va processivity in response to substrate. Biophysical journal, 103 (4). pp. 728-737. ISSN 1542-0086. (doi:https://doi.org/10.1016/j.bpj.2012.07.033) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Dunn, Andrew R and Kad, Neil M and Nelson, Shane R and Warshaw, David M and Wallace, Susan S (2011) Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA. Nucleic acids research, 39 (17). pp. 7487-7498. ISSN 0305-1048. E-ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkr459) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Wang, Hong and Kennedy, Guy G and Warshaw, David M and Van Houten, Bennett (2010) Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Molecular cell, 37 (5). pp. 702-713. ISSN 1097-4164. (doi:https://doi.org/10.1016/j.molcel.2010.02.003) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Trybus, Kathleen M and Warshaw, David M (2008) Load and Pi control flux through the branched kinetic cycle of myosin V. The Journal of biological chemistry, 283 (25). pp. 17477-84. ISSN 0021-9258. E-ISSN 1083-351X. (doi:https://doi.org/10.1074/jbc.M800539200) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Patlak, Joseph B and Fagnant, Patricia M and Trybus, Kathleen M and Warshaw, David M (2007) Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin. Biophysical journal, 92 (5). pp. 1623-1631. ISSN 1542-0086. (doi:https://doi.org/10.1529/biophysj.106.097618) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Kim, Scott and Warshaw, David M and VanBuren, Peter and Baker, Josh E (2005) Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin. Proceedings of the National Academy of Sciences of the United States of America, 102 (47). pp. 16990-16995. ISSN 0027-8424. E-ISSN 1091-6490. (doi:https://doi.org/10.1073/pnas.0506326102) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Rovner, Arthur S and Fagnant, Patricia M and Joel, Peteranne B and Kennedy, Guy G and Patlak, Joseph B and Warshaw, David M and Trybus, Kathleen M (2003) A mutant heterodimeric myosin with one inactive head generates maximal displacement. The Journal of cell biology, 162 (3). pp. 481-488. ISSN 0021-9525. E-ISSN 1540-8140. (doi:https://doi.org/10.1083/jcb.200304023) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Myers, Sarah L and Smith, David P and Smith, D Alastair and Radford, Sheena E and Thomson, Neil H (2003) Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy. Journal of molecular biology, 330 (4). pp. 785-797. ISSN 0022-2836. (doi:https://doi.org/10.1016/S0022-2836(03)00583-7) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Jones, Susan and Manning, James and Kad, Neil M and Radford, Sheena E (2003) Amyloid-forming peptides from beta2-microglobulin-Insights into the mechanism of fibril formation in vitro. Journal of molecular biology, 325 (2). pp. 249-257. ISSN 0022-2836. (doi:https://doi.org/10.1016/S0022-2836(02)01227-5) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Thomson, N H and Smith, D P and Smith, D A and Radford, S E (2001) Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro. Journal of molecular biology, 313 (3). pp. 559-571. ISSN 0022-2836. (doi:https://doi.org/10.1006/jmbi.2001.5071) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

McParland, V J and Kad, Neil M and Kalverda, A P and Brown, A and Kirwin-Jones, P and Hunter, M G and Sunde, M and Radford, S E (2000) Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro. Biochemistry, 39 (30). pp. 8735-8746. ISSN 0006-2960. (doi:https://doi.org/10.1021/bi000276j) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Cliff, M J and Kad, Neil M and Hay, N and Lund, P A and Webb, M R and Burston, S G and Clarke, A R (1999) A kinetic analysis of the nucleotide-induced allosteric transitions of GroEL. Journal of molecular biology, 293 (3). pp. 667-684. ISSN 0022-2836. (doi:https://doi.org/10.1006/jmbi.1999.3138) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Ranson, N A and Cliff, M J and Clarke, A R (1998) Asymmetry, commitment and inhibition in the GroE ATPase cycle impose alternating functions on the two GroEL rings. Journal of molecular biology, 278 (1). pp. 267-278. ISSN 0022-2836. (doi:https://doi.org/10.1006/jmbi.1998.1704) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Book section

Kong, Muwen and Beckwitt, Emily C and Springall, Luke and Kad, Neil M and Van Houten, Bennett (2017) Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Time. In: Methods in Enzymology. Elsevier, pp. 213-257. ISBN 978-0-12-811469-8. (doi:https://doi.org/10.1016/bs.mie.2017.03.027) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
[img]

Wang, Jiangzhou and Barnett, J T and Pollard, M R and Kad, Neil M (2017) Integrating Optical Tweezers, DNA Tightropes, and Single-Molecule Fluorescence Imaging: Pitfalls and Traps. In: Single-Molecule Enzymology: Nanomechanical Manipulation and Hybrid Methods. Methods in Enzymology, 582 . Elsevier, pp. 171-192. ISBN 978-0-12-809310-8. E-ISBN 978-0-12-809503-4. (doi:https://doi.org/10.1016/bs.mie.2016.08.003) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
[img]

Springall, Luke and Inchingolo, Alessio V and Kad, Neil M (2016) DNA-Protein Interactions Studied Directly Using Single Molecule Fluorescence Imaging of Quantum Dot Tagged Proteins Moving on DNA Tightropes. In: Leake, Mark C., ed. Chromosome Architecture. Methods in Molecular Biology, 1431 . Springer, pp. 141-150. ISBN 978-1-4939-3629-8. E-ISBN 978-1-4939-3631-1. (doi:https://doi.org/10.1007/978-1-4939-3631-1_11) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
[img]

Kad, Neil M and Van Houten, Bennett (2012) Dynamics of lesion processing by bacterial nucleotide excision repair proteins. In: Progress in Molecular Biology and Translational Science. Elsevier, pp. 1-24. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Kad, Neil M and Radford, Sheena E. (2001) Partial unfolding as a precursor to amyloidosis: A discussion of the occurrence, role and implications. In: Lund, Peter A., ed. Molecular Chaperones in the Cell. Frontiers in Moelcular Biology (37). Oxford University Press. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Software

Kad, Neil M (2019) Program to create Mean Squared displacement data from diffusion. Microsoft Excel Text program. (Unpublished) (Full text available)
[img]

This list was generated on Tue Apr 16 12:07:58 2019 BST.