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Number of items: 32.

Article

Ma, Jianhui and Benitez, Jorge A and Li, Jie and Miki, Sunichiro and Ponte de Alberquerque, Claudio and Galatro, Thais and Orellana, Laura and Zanca, Ciro and Reed, Rachel and Boyer, Antonia and Koga, Tomoyuki and Varki, Nissi M and Fenton, TR and Marie, SK and Lindahl, Erik and Gahman, Timothy C. and Shiau, Andrew K. and Zhou, Huilin and deGroot, John and Sulman, Erik P. and Cavenee, Webster K. and Kolodner, Richard D. and Chen, Clark C. and Furnari, FB (2019) Inhibition of nuclear PTEN tyrosine phosphorylation enhances glioma radiation sensitivity through attenuated DNA repair. Cancer Cell, . ISSN 1535-6108. (doi:https://doi.org/10.1016/j.ccell.2019.01.020) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Lechner, Matt and Chakravarthy, Ankur R. and Walter, Vonn and Masterson, Liam and Feber, Andrew and Jay, Amrita and Weinberger, Paul M. and McIndoe, Richard A. and Forde, Cillian T. and Chester, Kerry and Kalavrezos, Nicholas and O'Flynn, Paul and Forster, Martin and Jones, Terry M. and Vaz, Francis M. and Hayes, D. Neil and Fenton, TR (2018) Frequent HPV-independent p16/INK4A overexpression in head and neck cancer. Oral Oncology, 83 . pp. 32-37. ISSN 1368-8375. (doi:https://doi.org/10.1016/j.oraloncology.2018.06.006) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Periyasamy, Manikandan and Singh, Anup K. and Gemma, Carolina and Kranjec, Christian and Farzan, Raed and Leach, Damien A. and Navaratnam, Naveenan and Pálinkás, Hajnalka L. and Vértessy, Beata G. and Fenton, TR and Doorbar, John and Fuller-Pace, Frances and Meek, David W. and Coombes, R. Charles and Buluwela, Laki and Ali, Simak (2017) p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells. Nucleic Acids Research, 45 (19). pp. 11056-11069. ISSN 0305-1048. E-ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkx721) (Full text available)

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Chakravarthy, A and Henderson, S and Thirdborough, SM and Ottensmeier, CH and Su, X and Lechner, M and Feber, A and Thomas, GJ and Fenton, TR (2016) Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. Journal Of Clinical Oncology, 34 (34). pp. 4132-4141. ISSN 0732-183X. (doi:https://doi.org/10.1200/JCO.2016.68.2955) (Full text available)

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Masterson, L and Lechner, M and Loewenbein, S and Mohammed, H and Davies-Husband, C and Fenton, TR and Sudhoff, H and Jani, P and Goon, P and Sterling, J (2016) CD8+ T cell response to human papillomavirus 16 E7 is able to predict survival outcome in oropharyngeal cancer. European Journal of Cancer, 67 (C). pp. 141-151. ISSN 0959-8049. (doi:https://doi.org/10.1016/j.ejca.2016.08.012) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Feber, A and Worth, DC and Chakravarthy, A and de Winter, P and Shah, K and Arya, M and Saqib, M and Nigam, R and Malone, PR and Tan, WS and Rodney, S and Freeman, A and Jameson, C and Wilson, GA and Powles, T and Beck, S and Fenton, TR and Sharp, TV and Muneer, A and Kelly, JD (2016) CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma. Cancer Research, 76 (16). pp. 4720-4727. ISSN 0008-5472. (doi:https://doi.org/10.1158/0008-5472.CAN-15-3134) (Full text available)

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Campbell, J and Ryan, CJ and Brough, R and Bajrami, I and Pemberton, HN and Chong, IY and Costa-Cabral, S and Frankum, J and Gulati, A and Holme, H and Miller, R and Postel-Vinay, S and Rafiq, R and Wei, W and Williamson, CT and Quigley, DA and Tym, J and Al-Lazikani, B and Fenton, TR and Natrajan, R and Strauss, SJ and Ashworth, A and Lord, CJ (2016) Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell Reports, 14 (10). pp. 2490-2501. ISSN 2211-1247. (doi:https://doi.org/10.1016/j.celrep.2016.02.023) (Full text available)

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Henderson, S and Fenton, TR (2015) APOBEC3 genes: retroviral restriction factors to cancer drivers. Trends in Molecular Medicine, 21 (5). pp. 274-284. ISSN 1471-4914. (doi:https://doi.org/10.1016/j.molmed.2015.02.007) (Full text available)

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Chakravarthy, A and Henderson, S and Fenton, TR (2014) When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer. Molecular & Cellular Oncology, 1 (1). e29914 - e29914. ISSN 2372-3556. (doi:https://doi.org/10.4161/mco.29914) (Full text available)

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Henderson, S and Chakravarthy, A and Su, X and Boshoff, C and Fenton, TR (2014) APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development. Cell reports, 7 (6). pp. 1833-1841. ISSN 2211-1247. (doi:https://doi.org/10.1016/j.celrep.2014.05.012) (Full text available)

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Feber, A and Guilhamon, P and Lechner, M and Fenton, TR and Wilson, GA and Thirlwell, C and Morris, TJ and Flanagan, AM and Teschendorff, AE and Kelly, JD and Beck, S (2014) Using high-density DNA methylation arrays to profile copy number alterations. Genome Biology, 15 (2). ISSN 1474-760X. (doi:https://doi.org/10.1186/gb-2014-15-2-r30) (Full text available)

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Wilson, GA and Lechner, M and and H Carén, A Köferle and Butcher, LM and Feber, A and Fenton, TR and Jay, A and Boshoff, C and Beck, S (2013) Integrated virus-host methylome analysis in head and neck squamous cell carcinoma. Epigenetics, 8 (9). pp. 953-961. ISSN 1559-2294. (doi:https://doi.org/10.4161/epi.25614) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Lechner, M and Frampton, G and Fenton, TR and Feber, A and Palmer, G and Jay, A and Pillay, N and Forster, M and Cronin, MT and Lipson, D and Miller, VA and Brennan, TA and Henderson, S and Vaz, F and Flynn, P O 8217 and Kalavrezos, N and Yelenski, R and Beck, S and Stephens, PJ and Boshoff, C (2013) Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors. Genome Medicine, 5 . ISSN 1756-994X. (doi:https://doi.org/10.1186/gm453) (Full text available)

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Read, RD and Fenton, TR and Gomez, GG and Wykosky, J and Vandenberg, SR and Babic, I and Yang, H and Iwanami, A and Cavenee, WK and Mischel, PS and Furnari, FB and Thomas, JB (2013) A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma. PLoS Genetics, 9 (2). pp. 1-19. ISSN 1553-7390. E-ISSN 1553-7404. (doi:https://doi.org/10.1249/MSS.0b013e31822cb0d2) (Full text available)

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Lechner, M and Fenton, TR and West, J and Wilson, G and Feber, A and Henderson, S and Thirlwell, C and Dibra, HK and Jay, A and Butcher, L and Chakravarthy, AR and Gratrix, F and Patel, N and Vaz, F and O'Flynn, P and Kalavrezos, N and Teschendorff, AE and Boshoff, C and Beck, S (2013) Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma. Genome Medicine, 5 (2). ISSN 1756-994X. (doi:https://doi.org/10.1186/gm419) (Full text available)

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Fenton, TR and Nathanson, D and de Albuquerque, C Ponte and Kuga, D and Iwanami, A and Dang, J and Yang, H and Tanaka, K and Oba-Shinjo, SM and Uno, M and Inda, MM and Wykosky, J and Bachoo, RM and James, CD and DePinho, RA and Vandenberg, SR and Zhou, H and Marie, SK and Mischel, PS and Cavenee, WK and Furnari, FB (2012) Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proceedings of the National Academy of Sciences, 109 (35). 14164 - 14169. ISSN 0027-8424. (doi:https://doi.org/10.1073/pnas.1211962109) (Full text available)

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Feng, H and Hu, B and Jarzynka, MJ and Li, Y and Keezer, S and Johns, TG and Tang, CK and Hamilton, RL and Vuori, K and Nishikawa, R and Sarkaria, JN and Fenton, TR and Cheng, T and Furnari, FB and Cavenee, WK and Cheng, S-Y (2012) Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proceedings of the National Academy of Sciences, 109 (8). pp. 3018-3023. ISSN 1091-6490. (doi:https://doi.org/10.1073/pnas.1121457109) (Full text available)

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Feng, H and Hu, B and Liu, K-W and Li, Y and Lu, X and Cheng, T and Yiin, J-J and Lu, S and Keezer, S and Fenton, TR and Furnari, FB and Hamilton, RL and Vuori, K and Sarkaria, JN and Nagane, M and Nishikawa, R and Cavenee, WK and Cheng, S-Y (2011) Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFR\ensuremath?-stimulated glioma tumorigenesis in mice and humans. Journal of Clinical Investigation, 121 (12). pp. 4670-4684. ISSN 0021-9738. E-ISSN 1558-8238. (doi:https://doi.org/10.1172/JCI58559) (Full text available)

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Wykosky, J and Fenton, TR and Furnari, F and Cavenee, WK (2011) Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations. Chin J Cancer, 30 (1). pp. 5-12. (doi:https://doi.org/10.5732/cjc.010.10542) (Full text available)

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Fenton, TR and Gout, IT (2010) Functions and regulation of the 70 kDa ribosomal S6 kinases. International Journal of Biochemistry and Cell Biology, 43 (1). pp. 47-59. ISSN 1357-2725. E-ISSN 1878-5875. (doi:https://doi.org/10.1016/j.biocel.2010.09.018) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Fenton, TR and Gwalter, J and Cramer, R and Gout, IT (2010) S6K1 is acetylated at lysine 516 in response to growth factor stimulation. Biochemical and Biophysical Research Communications, 398 (3). 400 - 405. ISSN 0006-291X. (doi:https://doi.org/10.1016/j.bbrc.2010.06.081) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Fenton, TR and Gwalter, J and Ericsson, J and Gout, IT (2009) Histone acetyltransferases interact with and acetylate p70 ribosomal S6 kinases in vitro and in vivo. The International Journal of Biochemistry & Cell Biology, 42 (2). 359 - 366. ISSN 1357-2725. (doi:https://doi.org/10.1016/j.biocel.2009.11.022) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Wang, M-L and Panasyuk, G and Gwalter, J and Nemazanyy, I and Fenton, TR and Filonenko, V and Gout, I (2008) Regulation of ribosomal protein S6 kinases by ubiquitination. Biochemical and Biophysical Research Communications, 369 (2). pp. 382-387. ISSN 0006-291X. (doi:https://doi.org/10.1016/j.bbrc.2008.02.032) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Furnari, FB and Fenton, TR and Bachoo, RM and Mukasa, A and Stommel, JM and Stegh, A and Hahn, WC and Ligon, KL and Louis, DN and Brennan, C and Chin, L and DePinho, RA and Cavenee, WK (2007) Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev, 21 (21). pp. 2683-2710. (doi:https://doi.org/10.1101/gad.1596707) (Full text available)

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Carrasco, DR and Fenton, TR and Sukhdeo, K and Protopopova, M and Enos, M and You, MJ and Vizio, D Di and Nogueira, C and Stommel, J and Pinkus, GS and Fletcher, C and Hornick, JL and Cavenee, WK and Furnari, FB and Depinho, RA (2006) The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell, 9 (5). pp. 379-390. ISSN 1535-6108. E-ISSN 1878-3686. (doi:https://doi.org/10.1016/j.ccr.2006.03.028) (Full text available)

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Rebholz, H and Panasyuk, G and Fenton, TR and Nemazanyy, I and Valovka, T and Flajolet, M and Ronnstrand, L and Stephens, L and West, A and Gout, IT (2006) Receptor association and tyrosine phosphorylation of S6 kinases. FEBS J, 273 (9). 2023 - 2036. (doi:https://doi.org/10.1111/j.1742-4658.2006.05219.x) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Zhyvoloup, A and Nemazanyy, I and Panasyuk, G and Valovka, T and Fenton, TR and Rebholz, H and Wang, ML and Foxon, R and Lyzogubov, V and Usenko, V and Kyyamova, R and Gorbenko, O and Matsuka, G and Filonenko, V and Gout, IT (2003) Subcellular localization and regulation of coenzyme a synthase. Journal of Biological Chemistry, 278 (50). 50316 - 50321. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.M307763200) (Full text available)

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Valovka, T and Verdier, F and Cramer, R and Zhyvoloup, A and Fenton, TR and Rebholz, H and Wang, ML and Gzhegotsky, M and Lutsyk, A and Matsuka, G and Filonenko, V and Wang, LJ and Proud, CG and Parker, PJ and Gout, IT (2003) Protein kinase C phosphorylates ribosomal protein S6 kinase beta II and regulates its subcellular localization. MOL CELL BIOL, 23 (3). 852 - 863. (doi:https://doi.org/10.1128/MCB.23.3.852-863.2003) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Zhyvoloup, A and Nemazanyy, I and Babich, A and Panasyuk, G and Pobigailo, N and Vudmaska, M and Naidenov, V and Kukharenko, O and Palchevskii, S and Savinska, L and Ovcharenko, G and Verdier, F and Valovka, T and Fenton, TR and Rebholz, H and Wang, ML and Shepherd, P and Matsuka, G and Filonenko, V and Gout, IT (2002) Molecular cloning of CoA synthase - The missing link in CoA biosynthesis. Journal of Biological Chemistry, 277 (25). 22107 - 22110. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.C200195200) (Full text available)

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Salim, K and Fenton, TR and Bacha, J and Urien-Rodriguez, H and Bonnert, T and Skynner, HA and Watts, E and Kerby, J and Heald, A and Beer, M and McAllister, G and Guest, PC (2002) Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation. Journal of Biological Chemistry, 277 (18). pp. 15482-15485. ISSN 0021-9258. (doi:https://doi.org/10.1074/jbc.M201539200) (Full text available)

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Fordham-Skelton, AP and Chilley, P and Lumbreras, V and Reignoux, S and Fenton, TR and Dahm, CC and Pages, M and Gatehouse, JA (2002) A novel higher plant protein tyrosine phosphatase interacts with SNF1-related protein kinases via a KIS (kinase interaction sequence) domain. The Plant journal : for cell and molecular biology, 29 (6). pp. 705-715. ISSN 0960-7412. (doi:https://doi.org/10.1046/j.1365-313X.2002.01250.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Book section

Lechner, M and Fenton, TR (2016) Chapter One - The Genomics, Epigenomics, and Transcriptomics of HPV-Associated Oropharyngeal Cancer - Understanding the Basis of a Rapidly Evolving Disease. In: Advances in Genetics. Advances in Genetics, 93 . Elsevier, pp. 1-56. ISBN 978-0-12-805217-4. E-ISBN 978-0-12-804801-6. (doi:https://doi.org/10.1016/bs.adgen.2015.12.001) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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