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A study of the formation of amorphous calcium phosphate and hydroxyapatite on melt quenched Bioglass® using surface sensitive shallow angle X-ray diffraction

Martin, R.A., Twyman, H., Qiu, D., Knowles, J.C., Newport, Robert J. (2009) A study of the formation of amorphous calcium phosphate and hydroxyapatite on melt quenched Bioglass® using surface sensitive shallow angle X-ray diffraction. Journal of Materials Science: Materials in Medicine, 20 (4). pp. 883-888. ISSN 0957-4530. (doi:10.1007/s10856-008-3661-5) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:47142)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL
http://dx.doi.org/10.1007/s10856-008-3661-5

Abstract

Melt quenched silicate glasses containing calcium, phosphorous and alkali metals have the ability to promote bone regeneration and to fuse to living bone. These glasses, including 45S5 Bioglass® [(CaO)26.9(Na2O)24.4(SiO2)46.1(P2O5)2.6], are routinely used as clinical implants. Consequently there have been numerous studies on the structure of these glasses using conventional diffraction techniques. These studies have provided important information on the atomic structure of Bioglass® but are of course intrinsically limited in the sense that they probe the bulk material and cannot be as sensitive to thin layers of near-surface dissolution/growth. The present study therefore uses surface sensitive shallow angle X-ray diffraction to study the formation of amorphous calcium phosphate and hydroxyapatite on Bioglass® samples, pre-reacted in simulated body fluid (SBF). Unreacted Bioglass® is dominated by a broad amorphous feature around 2.2 Å−1 which is characteristic of sodium calcium silicate glass. After reacting Bioglass® in SBF a second broad amorphous feature evolves ~1.6 Å−1 which is attributed to amorphous calcium phosphate. This feature is evident for samples after only 4 h reacting in SBF and by 8 h the amorphous feature becomes comparable in magnitude to the background signal of the bulk Bioglass®. Bragg peaks characteristic of hydroxyapatite form after 1–3 days of reacting in SBF.

Item Type: Article
DOI/Identification number: 10.1007/s10856-008-3661-5
Additional information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Mater. Sci. Mater. Med. [Field not mapped to EPrints] C2 - 19083082 [Field not mapped to EPrints] AD - School of Physical Sciences, University of Kent, Ingram Building, Canterbury, Kent CT2 7NH, United Kingdom [Field not mapped to EPrints] AD - Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X 8LD, United Kingdom [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled keywords: Amorphous calcium phosphates, Atomic structures, Background signals, Bioglass, Bone regenerations, Bragg peaks, Bulk materials, Diffraction techniques, Living bones, Near surfaces, Silicate glass, Simulated body fluids, Sodium calcium silicate glass, Thin layers, X- ray diffractions, Apatite, Bone, Calcium, Calcium alloys, Diffraction, Glass, Hydroxyapatite, Light metals, Phosphorus, Silicates, Smelting, Sodium, Surfaces, X ray diffraction, Calcium phosphate, alkali metal, calcium, calcium phosphate, glass, hydroxyapatite, phosphorus 32, article, body fluid, bone regeneration, dissolution, implant, priority journal, X ray diffraction, Calcium Phosphates, Ceramics, Durapatite, Surface Properties, X-Ray Diffraction
Subjects: Q Science > QC Physics > QC173.45 Condensed Matter
Q Science > QD Chemistry > QD478 Solid State Chemistry
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Depositing User: Giles Tarver
Date Deposited: 16 Feb 2015 16:23 UTC
Last Modified: 16 Nov 2021 10:19 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/47142 (The current URI for this page, for reference purposes)
Newport, Robert J.: https://orcid.org/0000-0002-2365-992X
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