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Solvent-Induced High Fidelity Switching Between Two Discrete Supramolecules

Betancourt, Jose E., Martin-Hidalgo, Mariana, Gubala, Vladimir, Rivera, Jose M. (2009) Solvent-Induced High Fidelity Switching Between Two Discrete Supramolecules. Journal of the American Chemical Society, 131 (9). pp. 3186-3188. ISSN 1520-5126. (doi:10.1021/ja809612d) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1021/ja809612d

Abstract

Here we show the reversible high fidelity switching between two discrete self-assembled supramolecules made from a lipophilic 8-phenyl-2?-deoxyguanosine derivative induced by an indirect solvent effect. A hexadecameric supramolecule containing four stacked tetramers is formed in acetonitrile aided by higher potassium concentrations. When the amount of weakly solvated potassium decreases, due the lower activity of potassium iodide in chloroform, an octamer is formed after the dissociation of the two outer tetramers in the hexadecamer. The switching process results from an unprecedented subtle interplay between the activity of potassium iodide and the steric crowding within the self-assembled structure. Besides the possible applications in nanoconstruction, this phenomenon sheds light into the mechanism of formation of self-assembled supramolecules made from guanosine derivatives.

Item Type: Article
DOI/Identification number: 10.1021/ja809612d
Additional information: number of additional authors: 3;
Subjects: Q Science
R Medicine > RS Pharmacy and materia medica
Divisions: Faculties > Sciences > Medway School of Pharmacy
Depositing User: Stewart Brownrigg
Date Deposited: 07 Mar 2014 00:05 UTC
Last Modified: 29 May 2019 12:24 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/40399 (The current URI for this page, for reference purposes)
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