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2019

Deng, Yun and Kalfon, Jeremie and Chu, Dominique and von der Haar, Tobias (2019) Hidden patterns of codon usage bias across kingdoms. BioRxiv, . (In press) (doi:https://doi.org/10.1249/MSS.0b013e31822cb0d2) (Full text available)

Beal, David M and Bastow, Emma L. and Staniforth, Gemma L. and von der Haar, Tobias and Freedman, Robert B. and Tuite, Mick F. (2019) Quantitative Analyses of the Yeast Oxidative Protein Folding Pathway in Vitro and in Vivo. Antioxidants & Redox Signalling, . ISSN 1523-0864. (In press) (doi:https://doi.org/10.1089/ars.2018.7615) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Xie, Jianling and de Souza Alves, Viviane and von der Haar, Tobias and O'Keefe, Louise and Lenchine, Roman V and Jensen, Kirk B and Liu, Riu and Coldwell, Mark J and Wang, Xuemin and Proud, Christopher G. (2019) Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan. Current Biology, 29 . pp. 1-13. ISSN 0960-9822. (doi:https://doi.org/10.1016/j.cub.2019.01.029) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Jossé, Lyne and Singh, Tarun and von der Haar, Tobias (2019) Experimental determination of codon usage?dependent selective pressure on high copy?number genes in Saccharomyces cerevisiae. Yeast, 36 . pp. 43-51. ISSN 0749-503X. (doi:https://doi.org/10.1002/yea.3373) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

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2018

Dowling, James (2018) The Effect of the NADPH Oxidase YNO1 on Translational Fidelity. Master of Science by Research (MScRes) thesis, University of Kent,. (Full text available)

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Khan, Mohammad Farhan and Spurgeon, Sarah K. and von der Haar, Tobias (2018) Origins of robustness in translational control via eukaryotic translation initiation factor (eIF) 2. Journal of Theoretical Biology, 445 . pp. 92-102. ISSN 0022-5193. (doi:https://doi.org/10.1016/j.jtbi.2018.02.020) (Full text available)

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2017

Sampson, Connor Dereck David (2017) Intracellular detection and functional impact of protein synthesis errors in S. cerevisiae and E. coli. Master of Science by Research (MScRes) thesis, University of Kent,. (Full text available)

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Khan, Mohammad Farhan (2017) Robustness and Responsiveness in Eukaryotic Protein Synthesis. Doctor of Philosophy (PhD) thesis, University of Kent,. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

Bastide, Amandine and Peretti, Diego and Knight, John R.P. and Grosso, Stefano and Spriggs, Ruth V. and Pichon, Xavier and Sbarrato, Thomas and Roobol, Anne and Roobol, Jo and Vito, Davide and Bushell, Martin and von der Haar, Tobias and Smales, Christopher Mark and Mallucci, Giovanna R. and Willis, Anne E. (2017) RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3. Current Biology, 27 (5). pp. 638-650. ISSN 0960-9822. (doi:https://doi.org/10.1016/j.cub.2017.01.047) (Full text available)

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Saintas, Emily and Abrahams, Liam and Ahmed, Gulshan T and Ajakaiye, Anu-Oluwa M and AlHumaidi, Abdulaziz S H A M and Ashmore-Harris, Candice and Clark, Iain and Dura, Usha K and Fixmer, Carine N and Ike-Morris, Chinedu and Mato Prado, Mireia and Mccullough, Danielle and Mishra, Shishir and Schoeler, Katia M U and Timur, Husne and Williamson, Maxwell D C and Alatsatianos, Markella and Bahsoun, Basma and Blackburn, Edith and Hogwood, Catherine E.M. and Lithgow, Pamela E and Rowe, Michelle L. and Yiangou, Lyto and Rothweiler, Florian and Cinatl jr, Jindric and Zehner, Richard and Baines, Anthony J. and Garrett, Michelle D. and Gourlay, Campbell W. and Griffin, Darren K. and Gullick, William J. and Hargreaves, Emma and Howard, Mark J. and Lloyd, Daniel R. and Rossman, Jeremy S. and Smales, Christopher Mark and Tsaousis, Anastasios D. and von der Haar, Tobias and Wass, Mark N. and Michaelis, Martin (2017) Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS. PLoS ONE, 12 (2). e0172140. ISSN 1932-6203. (doi:https://doi.org/10.1371/journal.pone.0172140) (Full text available)

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von der Haar, Tobias and Leadsham, Jane E. and Sauvadet, Aimie and Tarrant, Daniel.S.J and Adam, Ilectra S. and Saromi, Kofo and Laun, Peter and Rinnerthaler, Mark and Breitenbach-Koller, Hannelore and Breitenbach, Michael and Tuite, Mick F. and Gourlay, Campbell W. (2017) The control of translational accuracy is a determinant of healthy ageing in yeast. Open Biology, 7 (1). p. 160291. ISSN 2046-2441. (doi:https://doi.org/10.1098/rsob.160291) (Full text available)

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2016

Tuite, Mick F. and von der Haar, Tobias (2016) Transfer RNA in Decoding and the Wobble Hypothesis. In: eLS. Wiley, pp. 1-7. E-ISBN 978-0-470-01590-2. (doi:https://doi.org/10.1002/9780470015902.a0001497.pub2) (Full text available)

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Tarrant, Daniel J. and Stirpe, Mariarita and Rowe, Michelle and Howard, Mark J. and von der Haar, Tobias and Gourlay, Campbell W. (2016) Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism. Journal of Cell Science, 129 . pp. 4455-4465. ISSN 0021-9533. E-ISSN 1477-9137. (doi:https://doi.org/10.1242/jcs.192831) (Full text available)

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2015

Ji, Hong-Long (2015) Fibrinolytic Regulation of Pulmonary Epithelial Sodium Channels: a Critical Review. Doctor of Philosophy (PhD) thesis, University of Kent,. (Full text available)

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Beznoskova, Petra and Wagner, Susan and Jansen, Myrte E and von der Haar, Tobias and Valasek, Leos S (2015) Translation initiation factor eIF3 promotes programmed stop codon readthrough. Nucleic Acids Research, 43 (10). pp. 5099-5111. ISSN 0305-1048. (doi:https://doi.org/10.1093/nar/gkv421) (Full text available)

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Tarrant, Daniel.S.J (2015) Investigating the effects of increased levels of the translation elongation factor eEF1A within eukaryotic cells. Doctor of Philosophy (PhD) thesis, University of Kent,. (Full text available)

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Blanchet, Sandra and Rowe, Michelle and von der Haar, Tobias and Fabret, Céline and Demais, Stéphane and Howard, Mark J. and Namy, Olivier (2015) New insights into stop codon recognition by eRF1. Nucleic Acids Research, 43 (6). pp. 3298-3308. ISSN 0305-1048. (doi:https://doi.org/10.1093/nar/gkv154) (Full text available)

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2014

Smethurst, Daniel George Jan (2014) The dynamic status of actin in the regulation of environmental sensing and homeostatic control in Saccharomyces cerevisiae. Doctor of Philosophy (PhD) thesis, University of Kent,. (Full text available)

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Chu, Dominique and Thompson, James and von der Haar, Tobias (2014) Charting the dynamics of translation. Bio Systems, 119 (1). pp. 1-9. ISSN 1872-8324. (doi:https://doi.org/10.1016/j.biosystems.2014.02.005) (Full text available)

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Chu, Dominique and Kazana, Eleanna and Bellanger, Noémie and Singh, Tarun and Tuite, Mick F. and von der Haar, Tobias (2014) Translation elongation can control translation initiation on eukaryotic mRNAs. EMBO Journal, 33 (1). pp. 21-34. ISSN 0261-4189. (doi:https://doi.org/10.1002/embj.201385651) (Full text available)

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2013

Beznoskova, Petra and Cuchalova, Lucie and Wagner, Susan and Shoemaker, Christopher J and Gunisova, Stanislava and von der Haar, Tobias and Valasek, Leos S (2013) Translation Initiation Factors eIF3 and HCR1 Control Translation Termination and Stop Codon Read-Through in Yeast Cells. PLoS Genetics, 9 (11). e1003962. ISSN 1553-7404. (doi:https://doi.org/10.1371/journal.pgen.1003962) (Full text available)

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Hopker, James G. and Coleman, Damian A and Gregson, Hannah C and Jobson, Simon A. and von der Haar, Tobias and Wiles, Jonathan and Passfield, Louis (2013) The influence of training status, age, and muscle fiber type on cycling efficiency and endurance performance. Journal of Applied Physiology, 115 (5). pp. 723-729. ISSN 8750-7587. (doi:https://doi.org/10.?1152/?japplphysiol.?00361.?2013) (Full text available)

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Preiss, Thomas and Bauer, Johann W. and Brandl, Clemens and Haubenreisser, Olaf and Wimmer, Bjoern and Weber, Manuela and Karl, Thomas and Klausegger, Alfred and Breitenbach, Michael and Hintner, Helmut and von der Haar, Tobias and Tuite, Mick F. and Breitenbach-Koller, Lore (2013) Specialized Yeast Ribosomes: A Customized Tool for Selective mRNA Translation. PLoS ONE, 8 (7). e67609. ISSN 1932-6203. (doi:https://doi.org/10.1371/journal.pone.0067609) (Full text available)

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2012

Mead, Emma J and Chiverton, Lesley M. and Spurgeon, Sarah K. and Martin, Elaine B. and Montague, Gary A. and Smales, Christopher Mark and von der Haar, Tobias (2012) Experimental and In Silico Modelling Analyses of the Gene Expression Pathway for Recombinant Antibody and By-Product Production in NS0 Cell Lines. PLoS ONE, 7 (10). e47422. ISSN 1932-6203. (doi:https://doi.org/10.1371/journal.pone.0047422) (Full text available)

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von der Haar, Tobias (2012) Mathematical and Computational Modelling of Ribosomal Movement and Protein Synthesis: an overview. Computational and Structural Biotechnology Journal, 1 (1). e201204002. ISSN 2001-0370. (doi:https://doi.org/10.5936/csbj.201204002) (Full text available)

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Chu, Dominique and von der Haar, Tobias (2012) The architecture of eukaryotic translation. Nucleic Acids Research, 40 (20). pp. 10098-10106. ISSN 0305-1048. (doi:https://doi.org/10.1093/nar/gks825) (Full text available)

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2011

Chu, Dominique and Barnes, David J. and von der Haar, Tobias (2011) The role of tRNA and ribosome competition in coupling the expression of different mRNAs in Saccharomyces cerevisiae. Nucleic Acids Research, 39 (15). pp. 6705-6714. ISSN 0305-1048. (doi:https://doi.org/10.1093/nar/gkr300) (Full text available)

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2010

Merritt, Gloria H. and Naemi, Wesley R. and Mugnier, Pierre M. and Webb, Helen M. and Tuite, Mick F. and von der Haar, Tobias (2010) Decoding accuracy in eRF1 mutants and its correlation with pleiotropic quantitative traits in yeast. Nucleic acids research, 38 (16). pp. 5479-5492. ISSN 1362-4962. (doi:https://doi.org/10.1093/nar/gkq338) (Full text available)

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2009

von der Haar, Tobias (2009) One for all? A viral protein supplants the mRNA cap-binding complex. Embo Journal, 28 (1). pp. 6-7. ISSN 0261-4189. (doi:https://doi.org/10.1038/emboj.2008.251) (Full text available)

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2008

von der Haar, Tobias (2008) A quantitative estimation of the global translational activity in logarithmically growing yeast cells. BMC Systems Biology, 2 . ISSN 1752-0509. (doi:https://doi.org/10.1186/1752-0509-2-87) (Full text available)

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2007

McCarthy, John E. G. and Marsden, Steven and von der Haar, Tobias (2007) Biophysical studies of the translation initiation pathway using immobilised mRNA analogues. In: Lorsch, J., ed. Translation Initiation: Reconstituted Systems and Biophysical Methods. Methods in Enzymology (Volume). Elsevier, pp. 247-264. ISBN 978-0-12-373969-8. (doi:https://doi.org/10.1016/S0076-6879(07)30010-4) (Full text available)

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von der Haar, Tobias (2007) Optimized protein extraction for quantitative proteomics of yeasts. PLoS ONE, 2 (10). e1078. ISSN 1932-6203. (doi:https://doi.org/10.1371/journal.pone.0001078) (Full text available)

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Gilbert, Robert J.C. and Gordiyenko, Yulya and von der Haar, Tobias and Sonnen, Andreas F.P. and Hofmann, Gregor and Nardelli, Maria and Stuart, David I. and McCarthy, John E. G. (2007) Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex. Proceedings of the National Academy of Sciences of the United States of America, 104 (14). pp. 5788-5793. ISSN 0027-8424. (doi:https://doi.org/10.1073/pnas.0606880104) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

2006

von der Haar, Tobias and Oku, Yuko and Ptushkina, Marina and Moerke, Nathan and Wagner, Gerhard and Gross, John D. and McCarthy, John E. G. (2006) Folding transitions during assembly of the eukaryotic mRNA cap-binding complex. Journal of Molecular Biology, 356 . pp. 982-992. (doi:https://doi.org/10.1016/j.jmb.2005.12.034) (Full text available)

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2004

von der Haar, Tobias and Gross, John D. and Wagner, Gerhard and McCarthy, John E. G. (2004) The mRNA cap-binding protein eIF4E in post-transcriptional gene expression. Nature Structural and Molecular Biology, 11 (6). pp. 503-511. ISSN 1545-9985. (doi:https://doi.org/10.1038/nsmb779) (Full text available)

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2003

Gross, John D. and Moerke, Nathan and von der Haar, Tobias and Lugovskoy, A.A. and Sachs, A.B. and McCarthy, John E. G. and Wagner, Gerhard (2003) Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell, 115 . pp. 739-750. ISSN 0092-8674. E-ISSN 1097-4172. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

He, Hui and von der Haar, Tobias (2003) The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection. Molecular and Cellular Biology, 23 . pp. 5431-5445. ISSN 0270-7306. E-ISSN 1098-5549. (doi:https://doi.org/10.1128/MCB.23.15.5431-5445.2003) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

2002

von der Haar, Tobias and McCarthy, John E. G. (2002) Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function. Molecular Microbiology, 46 . pp. 531-544. ISSN 0950-382X. E-ISSN 1365-2958. (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)

2001

2000