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Number of items: 55.

Article

Curtis-Marof, Rose and Doko, Denisa and Rowe, Michelle L. and Richards, Kirsty L. and Williamson, Richard A. and Howard, Mark J. (2014) 19F NMR spectroscopy monitors ligand binding to recombinantly fluorine-labelled b′x from human protein disulphide isomerase (hPDI). Organic & Biomolecular Chemistry, 12 (23). pp. 3808-3812. ISSN 1477-0520. (The full text of this publication is not available from this repository)

Ley, Nathan B. and Rowe, Michelle L. and Williamson, Richard A. and Howard, Mark J. (2014) Optimising selective excitation pulses to maximise saturation transfer difference NMR spectroscopy. RSC Advances, 4 (14). pp. 7347-7351. ISSN 2046-2069. (The full text of this publication is not available from this repository)

Irvine, Alistair G. and Wallis, Anne Katrine and Sanghera, Narinder and Rowe, Michelle L. and Ruddock, Lloyd W. and Howard, Mark J. and Williamson, Richard A. and Blindauer, Claudia A. and Freedman, Robert B. (2014) Protein Disulfide-Isomerase Interacts with a Substrate Protein at All Stages along Its Folding Pathway. PLoS ONE, 9 (1). e82511. ISSN 1932-6203. (The full text of this publication is not available from this repository)

Taylor, Samantha L. and Crawley-Snowdon, Harriet and Wagstaff, Jane L. and Rowe, Michelle L. and Shepherd, Mark and Williamson, Richard A. and Howard, Mark J. (2013) Measuring protein reduction potentials using 15N HSQC NMR spectroscopy. Chemical Communications, 49 (18). pp. 1847-1849. ISSN 1359-7345 . (Full text available)
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Amin, Nader T. and Wallis, Anne Katrine and Wells, Stephen A. and Rowe, Michelle L. and Williamson, Richard A. and Howard, Mark J. and Freedman, Robert B. (2013) High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility. Biochemical Journal, 450 (2). pp. 321-332. ISSN 0264-6021. (The full text of this publication is not available from this repository)

Wagstaff, Jane L. and Rowe, Michelle L. and Hsieh, Shu-Ju and DiCara, Danielle and Marshall, John F. and Williamson, Richard A. and Howard, Mark J. (2012) NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin avb6 ligand specificity. RSC Advances, 2 (29). pp. 11019-11028. ISSN 2046-2069. (Full text available)
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McVicker, Gareth and Sun, Lei and Sohanpal, Baljinder K. and Gashi, Krishna and Williamson, Richard A. and Plumbridge, Jacqueline A. and Blomfield, Ian C. (2011) SlyA Protein Activates fimB Gene Expression and Type 1 Fimbriation in Escherichia coli K-12. Journal of Biological Chemistry, 286 (37). pp. 32026-32035. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Schmidt, Jürgen M. and Zhou, Shen and Rowe, Michelle L. and Howard, Mark J. and Williamson, Richard A. and Löhr, Frank (2011) One-bond and two-bond J couplings help annotate protein secondary-structure motifs: J-coupling indexing applied to human endoplasmic reticulum protein ERp18. Proteins: Structure, Function, and Bioinformatics, 79 (2). pp. 428-443. ISSN 0887-3585. (The full text of this publication is not available from this repository)

Wagstaff, Jane L. and Howard, Mark J. and Williamson, Richard A. (2010) Production of recombinant isotopically labelled peptide by fusion to an insoluble partner protein: generation of integrin alphavbeta6 binding peptides for NMR. Molecular BioSystems, 6 (12). pp. 2380-5. ISSN 1742-206X. (Full text available)
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Wagstaff, Jane L. and Howard, Mark J. and Williamson, Richard A. (2010) Production of recombinant isotopically labelled peptide by fusion to an insoluble partner protein: generation of integrin avß6 binding peptides for NMR. Molecular BioSystems, 6 (12). pp. 2380-2385. ISSN 1742-2051. (The full text of this publication is not available from this repository)

Williamson, Richard A. (2010) Refolding of TIMP-2 from Escherichia coli Inclusion Bodies. Methods in Molecular Biology, 622 . pp. 111-121. ISSN 1064-3745. (The full text of this publication is not available from this repository)

Wagstaff, Jane L. and Vallath, Sabari and Marshall, John F. and Williamson, Richard A. and Howard, Mark J. (2010) Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin alphavbeta6 protein-peptide interactions. Chemical Communications, 46 (40). pp. 7533-7535. ISSN 1359-7345. (Access to this publication is restricted)
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Wallis, Anne Katrine and Sidhu, Ateesh and Byrne, Lee J. and Howard, Mark J. and Ruddock, Lloyd W. and Williamson, Richard A. and Freedman, Robert B. (2009) The ligand-binding b' domain of human protein disulphide-isomerase mediates homodimerization. Protein Science, 18 (12). pp. 2569-2577. ISSN 0961-8368. (The full text of this publication is not available from this repository)

Byrne, Lee J. and Sidhu, Ateesh and Wallis, Anne Katrine and Ruddock, Lloyd W. and Freedman, Robert B. and Howard, Mark J. and Williamson, Richard A. (2009) Mapping of the ligand-binding site on the b' domain of human PDI: interaction with peptide ligands and the x-linker region. Biochemical Journal, 423 (2). pp. 209-217. ISSN 0264-6021. (Full text available)
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Rowe, Michelle L. and Ruddock, Lloyd W. and Kelly, Geoff and Schmidt, Jürgen M. and Williamson, Richard A. and Howard, Mark J. (2009) Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase. Biochemistry, 48 (21). pp. 4596-4606. ISSN 0006-2960 . (The full text of this publication is not available from this repository)

Nguyen, Van Dat and Wallis, Katrine and Howard, Mark J. and Haapalainen, Antti E. and Salo, Kirsi E. H. and Saaranen, Mirva J. and Sidhu, Ateesh and Wierenga, Rik K. and Freedman, Robert B. and Ruddock, Lloyd W. and Williamson, Richard A. (2008) Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain. Journal of Molecular Biology, 383 (5). pp. 1144-1155. ISSN 0022-2836 . (The full text of this publication is not available from this repository)

Lightbody, Kirsty L. and Ilghari, Dariush and Waters, Lorna C. and Carey, Gemma and Bailey, Mark A. and Williamson, Richard A. and Renshaw, Philip S. and Carr, Mark D. (2008) Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. Journal of Biological Chemistry, 283 (25). pp. 17681-17690. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Povey, Jane F. and Howard, Mark J. and Williamson, Richard A. and Smales, C. Mark (2008) The effect of peptide glycation on protein secondary structure. Journal of Structural Biology, 161 (2). pp. 151-161. ISSN 1047-8477. (Access to this publication is restricted)
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Williamson, Richard A. and Panagiotidou, Parthena and Mott, Joni D. and Howard, Mark J. (2008) Dynamic characterisation of the netrin-like domain of human type 1 procollagen C-proteinase enhancer and comparison to the N-terminal domain of tissue inhibitor of metalloproteinases (TIMP). Molecular Biosystems, 4 (5). pp. 417-425. ISSN 1742-206X . (The full text of this publication is not available from this repository)

Rapti, Magdalini and Knauper, Vera and Murphy, Gillian and Williamson, Richard A. (2006) Characterization of the AB loop region of TIMP-2. Involvement in pro-MMP-2 activation. Journal of Biological Chemistry, 281 . pp. 23386-23394. (Access to this publication is restricted)
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Alanen, Heli I. and Williamson, Richard A. and Howard, Mark J. and Hatahet, Feras S. and Salo, Kirsi E. H. and Kauppila, Annika and Kellokumpu, Sakari and Ruddock, Lloyd W. (2006) ERp27, a new non-catalytic endoplasmic reticulum-located human protein disulfide isomerase family member, interacts with ERp57. Journal of Biological Chemistry, 281 (44). pp. 33727-33738. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Renshaw, Philip S. and Lightbody, Kirsty L. and Veverka, Vaclav and Muskett, Frederick W. and Kelly, Geoff and Frenkiel, Tom A. and Gordon, Stephen V. and Hewinson, R. Glyn and Burke, Bernard and Norman, Jim and Williamson, Richard A. and Carr, Mark D. (2005) Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6. EMBO Journal, 24 . pp. 2491-2498. (Access to this publication is restricted)
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Lightbody, Kirsty L. and Renshaw, Philip S. and Collins, Michelle L. and Wright, Rebecca L. and Hunt, Debbie M. and Gordon, Stephen V. and Hewinson, R. Glyn and Buxton, Roger S. and Williamson, Richard A. and Carr, Mark D. (2004) Characterisation of complex formation between members of the Mycobacterium tuberculosis complex CFP-10/ESAT-6 protein family: towards an understanding of the rules governing complex formation and thereby functional flexibility. FEMS Microbiol Lett, 238 (1). pp. 255-262. ISSN 0378-1097. (The full text of this publication is not available from this repository)

Pirneskoski, Annamari and Klappa, Peter and Lobell, Mario and Williamson, Richard A. and Byrne, Lee J. and Alanen, Heli I. and Salo, Kirsi E. H. and Kivirikkos, Kari I. and Freedman, Robert B. and Ruddock, Lloyd W. (2004) Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase. Journal of Biological Chemistry, 279 (11). pp. 10374-10381. ISSN 0021-9258. (Access to this publication is restricted)
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Renshaw, Philip S. and Veverka, Vaclav and Kelly, Geoff and Frenkiel, Tom A. and Williamson, Richard A. and Gordon, Stephen V. and Hewinson, R. Glyn and Carr, Mark D. (2004) Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6. Journal of Biomolecular NMR, 30 (2). pp. 225-226. ISSN 0925-2738. (The full text of this publication is not available from this repository)

Jones, Gareth J.F. and Howard, Mark J. and McIntosh, Pauline and Williamson, Richard A. and Carr, Mark D. (2003) Sequence-specific assignment of the B-Myb DNA-binding domain (B-MybR2R3) bound to a 16 base-pair DNA target site corresponding to a regulatory site from the tom-1 gene. Journal of Biomolecular NMR, 26 (4). pp. 375-376. ISSN 0925-2738. (The full text of this publication is not available from this repository)

Alanen, Heli I. and Williamson, Richard A. and Howard, Mark J. and Lappi, Anna-Kaisa and Jantti, Heli P. and Rautio, Sini M. and Kellokumpu, Sakari and Ruddock, Lloyd W. (2003) Functional characterization of ERp18, a new endoplasmic reticulum-located thioredoxin superfamily member. Journal of Biological Chemistry, 278 (31). pp. 28912-28920. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Murphy, Gillian and Knauper, Vera and Lee, Meng-Huee and Amour, Augustin and Worley, Joanna R. and Hutton, Mike and Atkinson, Susan and Rapti, Magdalene and Williamson, Richard A. (2003) Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity is in the detail. Biochemical Society Symposia, 70 . pp. 65-80. ISSN 0067-8694. (The full text of this publication is not available from this repository)

Carr, Mark D. and Bloemink, Marieke J. and Dentten, Ellen and Whelan, Adam and Gordon, Stephen V. and Kelly, Geoff and Frenkiel, Tom A. and Hewinson, R. Glyn and Williamson, Richard A. (2003) Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease. Journal of Biological Chemistry, 278 . pp. 43736-43743. (Access to this publication is restricted)
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Renshaw, Philip S. and Panagiotidou, Parthena and Whelan, Adam and Gordon, Stephen V. and Hewinson, R. Glyn and Williamson, Richard A. and Carr, Mark D. (2002) Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence. Journal of Biological Chemistry, 277 (24). pp. 21598-21603. ISSN 0021-9258 . (The full text of this publication is not available from this repository)

Blower, Philip J. and Giersing, Birgitte K. and Rae, Michael T. and Brea, Montserat Carballido and Williamson, Richard A. (2001) Synthesis and Characterization of 111In−DTPA−N-TIMP-2:  A Radiopharmaceutical for Imaging Matrix Metalloproteinase Expression. Bioconjugate Chemistry, 12 (6). pp. 964-971. ISSN 1043-1802. (The full text of this publication is not available from this repository)

Kulasegaram, R. and Giersing, Birgitte K. and Page, C.J and Blower, Philip J. and Williamson, Richard A. and Peters, B.S. and O'Doherty, Michael J. (2001) In Vivo Evaluation of 111In-DTPA-N-TIMP-2 in Kaposi Sarcoma Associated with HIV Infection. European Journal of Nuclear Medicine, 28 (6). pp. 756-761. ISSN 0340-6997. (The full text of this publication is not available from this repository)

Williamson, Richard A. (2001) Refolding of TIMP-2 from Escherichia Coli Inclusion Bodies. Methods in Molecular Biology, 151 . pp. 257-265. ISSN 1064-3745. (The full text of this publication is not available from this repository)

Bloemink, Marieke J. and Kemmink, Johan and Dentten, Ellen and Muskett, Frederick W. and Whelan, Adam and Sheikh, Amina and Hewinson, Glyn and Williamson, Richard A. and Carr, Mark D. (2001) Sequence-specific assignment and determination of the secondary structure of the 163-residue M. tuberculosis and M. bovis antigenic protein mpb70. Journal of Biomolecular NMR, 20 (2). pp. 185-186. ISSN 0925-2738. (The full text of this publication is not available from this repository)

Giersing, Birgitte K. and Rae, Michael T. and CarballidoBrea, Monstserrat and Williamson, Richard A. and Blower, Philip J. (2001) Synthesis and Characterization of 111In-DTPA-N-TIMP-2: A Radiopharmaceutical for Imaging Matrix Metalloproteinase Expression. Bioconjugate Chemistry, 12 (6). pp. 964-971. ISSN 1043-1802. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Hutton, Mike and Vogt, Gavin and Rapti, Magdalene and Knauper, Vera and Carr, Mark D. and Murphy, Gillian (2001) Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14. Journal of Biological Chemistry, 276 . pp. 32966-32970. (Access to this publication is restricted)
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Blower, Philip J. and Giersing, Birgitte K. and Rae, Michael T. and Link, Eva M. and Kulasegaram, R. and O'Doherty, Michael J. and Page, C.J and Williamson, Richard A. (2000) Matrix metalloproteinases as a target for tumor imaging: In vivo evaluation of radiolabeled N-TIMP-2. Journal of Nuclear Medicine, 41 (5). 258P-258P . ISSN 0161-5505. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Muskett, Frederick W. and Howard, Mark J. and Freedman, Robert B. and Carr, Mark D. (1999) The effect of matrix metalloproteinase complex formation on the conformational mobility of tissue inhibitor of metalloproteinases-2 (TIMP-2). Journal of Biological Chemistry, 274 (52). pp. 37226-37232. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Butler, Georgina S. and Hutton, Mike and Wattam, Beth A. and Williamson, Richard A. and Knauper, Vera and Willenbrock, Frances and Murphy, Glynis H. (1999) The specificity of TIMP-2 for matrix metalloproteinases can be modified by single amino acid mutations. Journal of Biological Chemistry, 274 (29). pp. 20391-20396. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Hutton, Mike and Butler, Georgina S. and Wattam, Beth A. and Willenbrock, Frances and Williamson, Richard A. and Murphy, Gillian (1999) Analysis of the interaction of TIMP-2 and MMPs: engineering the changes. Annals of the New York Academy of Sciences, 878 . pp. 524-527. ISSN 0077-8923 . (The full text of this publication is not available from this repository)

Glaser, Matthias and Howard, Mark J. and Howland, Kevin and Powell, Anne K. and Rae, Michael T. and Wocadlo, Sigrid and Williamson, Richard A. and Blower, Philip J. (1998) Structural characterisation and bioconjugation of an active ester containing oxorhenium(V) complex incorporating a thioether donor. Journal of the Chemical Society-Dalton Transactions (18). pp. 3087-3092. ISSN 0300-9246. (The full text of this publication is not available from this repository)

Muskett, Frederick W. and Frenkiel, Tom A. and Feeney, James and Freedman, Robert B. and Carr, Mark D. and Williamson, Richard A. (1998) High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3. Journal of Biological Chemistry, 273 (34). pp. 21736-21743. ISSN 0021-9258. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Carr, Mark D. and Frenkiel, Tom A. and Feeney, James and Freedman, Robert B. (1997) Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation. Biochemistry, 36 (45). pp. 13882-13889. ISSN 0006-2960. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Natalia, Dessy and Gee, Christopher K. and Murphy, Gillian and Carr, Mark D. and Freedman, Robert B. (1996) Chemically and conformationally authentic active domain of human tissue inhibitor of metalloproteinases-2 refolded from bacterial inclusion bodies. European Journal of Biochemistry, 241 (2). pp. 476-483. ISSN 0014-2956. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Martorell, Gabriel and Carr, Mark D. and Murphy, Gillian and Docherty, Andrew J. P. and Freedman, Robert B. and Feeney, James (1994) Solution Strucure of the Active Domain of Tissue Inhitor of Metalloprotrinases.2.A new Member of the OB Fold Protein Family. Biochemistry, 33 (39). pp. 11745-11759. ISSN 0006-2960. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Bartels, Helga and Murphy, Gillian and Freedman, Robert B. (1994) Folding and Stability of the Active N-Terminal Domain of Tissue Inhibitor of Metalloproteinse-1 and Metalloproteinase-1 and Metalloproteinase-2. Protein Engineering, 7 (8). pp. 1035-1040. ISSN 0269-2139. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Bartels, Helga and Murphy, Glynis H. and Freedman, Robert B. (1994) Folding and stability of the active N-terminal domain of tissue inhibitor of metalloproteinases-1 and -2. Protein Engineering, 7 (8). pp. 1035-1040. ISSN 0269-2139. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Smith, Bryan J. and Angal, Sarojani and Freedman, Robert B. (1993) Chemical modification of tissue inhibitor of metalloproteinases-1 and its inactivation by diethyl pyrocarbonate. Biochimica Et Biophysica Acta, 1203 (1). pp. 147-154. ISSN 0006-3002. (The full text of this publication is not available from this repository)

Williamson, Richard A. and Smith, Bryan J. and Angal, Sarojani and Murphy, Gillian and Freedman, Robert B. (1993) Structural analysis of tissue inhibitor of metalloproteinases-1 (TIMP-1) by tryptic peptide mapping. Biochimica Et Biophysica Acta, 1164 (1). pp. 8-16. ISSN 0006-3002. (The full text of this publication is not available from this repository)

Oshea, Mark and Willenbrock, Frances and Williamson, Richard A. and Cockett, Mark I. and Freedman, Robert B. and Reynolds, John J. and Docherty, Andrew J. P. and Murphy, Gillian (1992) Site-Directed Mutations That Alter the Inhibitory Activity of the Tissue Inhibitor of Metalloproteinases-1 - Importance of the N-Terminal Region between Cysteine-3 and Cysteine-13. Biochemistry, 31 (42). pp. 10146-10152. ISSN 0006-2960. (The full text of this publication is not available from this repository)

Murphy, Gillian and Houbrechts, Annick and Cockett, Mark I. and Williamson, Richard A. and O'Shea, Mark and Docherty, Andrew J. P. (1991) The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity. Biochemistry, 30 (33). pp. 8097-8102. ISSN 0006-2960 . (The full text of this publication is not available from this repository)

Williamson, Richard A. and Marston, Fiona A. and Angal, Sarojani and Koklitis, P. and Panico, M. and Morris, Howard R. and Carne, A.F. and Smith, B.J. and Harris, T.J. and Freedman, Robert B. (1990) Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP). Biochemical Journal, 268 (2). pp. 267-274. ISSN 0264-6021 . (The full text of this publication is not available from this repository)

Datasets / databases

Rowe, Michelle L. and Ruddock, Lloyd W. and Kelly, Geoff and Schmidt, Jürgen M. and Williamson, Richard A. and Howard, Mark J. (2009) Solution structure of Oxidised ERp18. RSCB/PDB Protein Data Bank PDB formatted text file. 8.1MB. Located at: http://www.rcsb.org/pdb/explore/explore.do?pdbId=2K8V. 10.2210/pdb2k8v/pdb. (The full text of this publication is not available from this repository)

Rowe, Michelle L. and Alanen, Heli I. and Ruddock, Lloyd W. and Kelly, Geoff and Schmidt, Jürgen M. and Williamson, Richard A. and Howard, Mark J. (2009) 1H, 13C, 15N chemical shift assignments for oxidised ERp18. Biological Magnetic Resonance Data Bank (BMRB), Madison, Wisconsin, USA NMR-STAR formatted text file. 102kB. Located at: http://www.bmrb.wisc.edu/data_library/generate_summary.php?bmrbId=15964. BMRB entry 15964. (The full text of this publication is not available from this repository)

Rowe, Michelle L. and Alanen, Heli I. and Ruddock, Lloyd W. and Kelly, Geoff and Schmidt, Jürgen M. and Williamson, Richard A. and Howard, Mark J. (2009) 1H, 13C, 15N chemical shift assignments for reduced ERp18. Biological Magnetic Resonance Data Bank (BMRB), Madison, Wisconsin, USA NMR-STAR formatted text file. 53kB. Located at: http://www.bmrb.wisc.edu/data_library/generate_summary.php?bmrbId=7430. BMRB entry 7430. (The full text of this publication is not available from this repository)

This list was generated on Mon Jul 28 09:47:01 2014 BST.