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Number of items: 48.

Article

Howard, M.J. (2013) Measuring protein reduction potentials using 15N HSQC NMR spectroscopy. Chemical Communications, 49 (18). pp. 1847-1849. ISSN 1359-7345 . Access to this publication is restricted.

Schmidt, J.M. and Zhou, S. and Rowe, M.L. and Howard, M.J. and Williamson, R.A. and Löhr, F. (2011) One-bond and two-bond J couplings help annotate protein secondary-structure motifs: J-coupling indexing applied to human endoplasmic reticulum protein ERp18. Proteins: Structure, Function, and Bioinformatics, 79 (2). pp. 428-443. ISSN 0887-3585. The full text of this publication is not available from this repository.

Wagstaff, J.L. and Rowe, M.L. and Hsieh, Shu-Ju and DiCara, D. and Marshall, J.F. and Williamson, R.A. and Howard, Mark J (2010) NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin avb6 ligand specificity. RSC Advances, 2 (n/a). pp. 11019-11028. ISSN 2046-2069.

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Wagstaff, J.L. and Howard, M.J. and Williamson, R.A. (2010) Production of recombinant isotopically labelled peptide by fusion to an insoluble partner protein: generation of integrin alphavbeta6 binding peptides for NMR. Mol Biosyst, 6 (12). pp. 2380-5. ISSN 1742-2051 (Electronic)1742-2051 (Linking).

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Wagstaff, J.L. and Vallath, S. and Marshall, J.F. and Williamson, R.A. and Howard, M.J. (2010) Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin alphavbeta6 protein-peptide interactions. Chem Commun (Camb), 46 (40). pp. 7533-7535. ISSN 1359-7345. Access to this publication is restricted.

Wallis, A.K. and Sidhu, A. and Byrne, L.J. and Howard, M.J. and Ruddock, L.W. and Williamson, R.A. and Freedman, R.B. (2009) The ligand-binding b' domain of human protein disulphide-isomerase mediates homodimerization. Protein Sci, 18 (12). pp. 2569-2577. ISSN 1469-896X. The full text of this publication is not available from this repository.

Byrne, L.J. and Sidhu, A. and Wallis, A.K. and Ruddock, L.W. and Freedman, R.B. and Howard, M.J. and Williamson, R.A. (2009) Mapping of the ligand-binding site on the b' domain of human PDI: interaction with peptide ligands and the x-linker region. Biochemical Journal, 423 (2). pp. 209-217. ISSN 1470-8728 (Electronic) 0264-6021 (Linking).

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Rowe, M.L. and Ruddock, L.W. and Kelly, G. and Schmidt, J.M. and Williamson, R.A. and Howard, M.J. (2009) Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase. Biochemistry, 48 (21). pp. 4596-4606. ISSN 0006-2960 . The full text of this publication is not available from this repository.

Nguyen, V.D. and Wallis, K. and Howard, M.J. and Haapalainen, A.M. and Salo, K.E. and Saaranen, M.J. and Sidhu, A. and Wierenga, R.K. and Freedman, R.B. and Ruddock, L.W. and Williamson, R.A. (2008) Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain. Journal of Molecular Biology, 383 (5). pp. 1144-1155. ISSN 0022-2836 . The full text of this publication is not available from this repository.

Lightbody, K.L. and Ilghari, D. and Waters, L.C. and Carey, G. and Bailey, M.A. and Williamson, R.A. and Renshaw, P.S. and Carr, M.D. (2008) Molecular features governing the stability and specificity of functional complex formation by Mycobacterium tuberculosis CFP-10/ESAT-6 family proteins. Journal of Biological Chemistry, 283 (25). pp. 17681-17690. ISSN 0021-9258. The full text of this publication is not available from this repository.

Povey, J. and Howard, M.J. and Williamson, R.A. and Smales, C.M. (2008) The effect of peptide glycation on protein secondary structure. Journal of Structural Biology, 161 (2). pp. 151-161. ISSN 1047-8477. Access to this publication is restricted.

Williamson, R.A. and Panagiotidou, P. and Mott, J.D. and Howard, M.J. (2008) Dynamic characterisation of the netrin-like domain of human type 1 procollagen C-proteinase enhancer and comparison to the N-terminal domain of tissue inhibitor of metalloproteinases (TIMP). Molecular Biosystems, 4 (5). pp. 417-425. ISSN 1742-206X . The full text of this publication is not available from this repository.

Rapti, M. and Knauper, V. and Murphy, G. and Williamson, R.A. (2006) Characterization of the AB loop region of TIMP-2. Involvement in pro-MMP-2 activation. Journal of Biological Chemistry, 281 . pp. 23386-23394. Access to this publication is restricted.

Alanen, H.I. and Williamson, R.A. and Howard, M.J. and Hatahet, F.S. and Salo, K.E. and Kauppila, A. and Kellokumpu, S. and Ruddock, L.W. (2006) ERp27, a new non-catalytic endoplasmic reticulum-located human protein disulfide isomerase family member, interacts with ERp57. J Biol Chem, 281 (44). pp. 33727-33738. ISSN 0021-9258. The full text of this publication is not available from this repository.

Renshaw, P.S. and Lightbody, K.L. and Veverka, V. and Muskett, F.W. and Kelly, G. and Frenkiel, T.A. and Gordon, S.V. and Hewinson, R.G. and Burke, B. and Norman, J. and Williamson, R.A. and Carr, M.D. (2005) Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6. EMBO Journal, 24 . pp. 2491-2498. Access to this publication is restricted.

Lightbody, K.L. and Renshaw, P.S. and Collins, M.L. and Wright, R.L. and Hunt, D.M. and Gordon, S.V. and Hewinson, R.G. and Buxton, R.S. and Williamson, R.A. and Carr, M.D. (2004) Characterisation of complex formation between members of the Mycobacterium tuberculosis complex CFP-10/ESAT-6 protein family: towards an understanding of the rules governing complex formation and thereby functional flexibility. FEMS Microbiol Lett, 238 (1). pp. 255-262. ISSN 0378-1097. The full text of this publication is not available from this repository.

Pirneskoski, A. and Klappa, P. and Lobell, M. and Williamson, R.A. and Byrne, L. and Alanen, H.I. and Salo, K.E.H. and Kivirikkos, K.I. and Freedman, R.B. and Ruddock, L.W. (2004) Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase. Journal of Biological Chemistry, 279 (11). pp. 10374-10381. ISSN 0021-9258. Access to this publication is restricted.

Renshaw, P.S. and Veverka, V. and Kelly, G. and Frenkiel, T.A. and Williamson, R.A. and Gordon, S.V. and Hewinson, R.G. and Carr, M.D. (2004) Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6. JOURNAL OF BIOMOLECULAR NMR, 30 (2). pp. 225-226. ISSN 0925-2738. The full text of this publication is not available from this repository.

Jones, G. and Howard, M.J. and McIntosh, P. and Williamson, R.A. and Carr, M.D. (2003) Sequence-specific assignment of the B-Myb DNA-binding domain (B-MybR2R3) bound to a 16 base-pair DNA target site corresponding to a regulatory site from the tom-1 gene. J Biomol NMR, 26 (4). pp. 375-376. ISSN 0925-2738 (Print). The full text of this publication is not available from this repository.

Alanen, H.I. and Williamson, R.A. and Howard, M.J. and Lappi, A.K. and Jantti, H.P. and Rautio, S.M. and Kellokumpu, S. and Ruddock, L.W. (2003) Functional characterization of ERp18, a new endoplasmic reticulum-located thioredoxin superfamily member. JOURNAL OF BIOLOGICAL CHEMISTRY, 278 (31). pp. 28912-28920. ISSN 0021-9258. The full text of this publication is not available from this repository.

Murphy, G. and Knauper, V. and Lee, M.H. and Amour, A. and Worley, J.R. and Hutton, M. and Atkinson, S. and Rapti, M. and Williamson, R.A. (2003) Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity is in the detail. Biochem Soc Symp, 70 . pp. 65-80. ISSN 0067-8694. The full text of this publication is not available from this repository.

Carr, M.D. and Bloemink, M.J. and Dentten, E. and Whelan, A.O. and Gordon, S.V. and Kelly, G. and Frenkiel, T.A. and Hewinson, R.G. and Williamson, R.A. (2003) Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease. Journal of Biological Chemistry, 278 . pp. 43736-43743. Access to this publication is restricted.

Renshaw, P.S. and Panagiotidou, P. and Whelan, A. and Gordon, S.V. and Hewinson, R.G. and Williamson, R.A. and Carr, M.D. (2002) Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence. Journal of Biological Chemistry, 277 (24). pp. 21598-21603. ISSN 0021-9258 . The full text of this publication is not available from this repository.

Blower, P.J. and Giersing, B.K. and Rae, M.T. and Brea, M.C. and Williamson, R.A. and O'Doherty, M.J. (2001) In-111-DTPA-N-TIMP-2: A radiopharmaceutical for imaging matrix metalloproteinase expression in tumors. BIOCONJUGATE CHEMISTRY , 12 (6). pp. 964-971. ISSN 1043-1802 . The full text of this publication is not available from this repository.

Kulasegaram, R. and Giersing, B.K. and Page, C.J. and Blower, P.J. and Williamson, R.A. and Peters, B.S. and O'Doherty, M.J. (2001) In Vivo Evaluation of 111In-DTPA-N-TIMP-2 in Kaposi Sarcoma Associated with HIV Infection. European Journal of Nuclear Medicine, 28 (6). pp. 756-761. ISSN 0340-6997. The full text of this publication is not available from this repository.

Williamson, R.A. (2001) Refolding of TIMP-2 from Escherichia Coli Inclusion Bodies. Methods in Molecular Biology, 151 . pp. 257-265. ISSN 1064-3745. The full text of this publication is not available from this repository.

Bloemink, M.J. and Kemmink, J. and Dentten, E. and Muskett, F.W. and Whelan, A. and Sheikh, A. and Hewinson, G. and Williamson, R.A. and Carr, M.D. (2001) Sequence-specific assignment and determination of the secondary structure of the 163-residue M. tuberculosis and M. bovis antigenic protein mpb70. J Biomol NMR, 20 (2). pp. 185-186. The full text of this publication is not available from this repository.

Giersing, B.K. and Rae, M.T. and CarballidoBrea, M. and Williamson, R.A. and Blower, P.J. (2001) Synthesis and Characterization of 111In-DTPA-N-TIMP-2: A Radiopharmaceutical for Imaging Matrix Metalloproteinase Expression. Bioconjug Chemistry, 12 (6). pp. 964-971. ISSN 1043-1802 . The full text of this publication is not available from this repository.

Williamson, R.A. and Hutton, M. and Vogt, G. and Rapti, M. and Knauper, V. and Carr, M.D. and Murphy, G. (2001) Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14. Journal of Biological Chemistry, 276 . pp. 32966-32970. Access to this publication is restricted.

Blower, P.J. and Giersing, B.K. and Rae, M.T. and Link, E.M. and Kulasegaram, R. and O'Doherty, M.J. and Page, C.J. and Williamson, R.A. (2000) Matrix metalloproteinases as a target for tumor imaging: In vivo evaluation of radiolabeled N-TIMP-2. Journal of Nuclear Medicine, 41 (5). 258P-258P . ISSN 0161-5505. The full text of this publication is not available from this repository.

Williamson, R.A. and Muskett, F.W. and Howard, M.J. and Freedman, R.B. and Carr, M.D. (1999) The effect of matrix metalloproteinase complex formation on the conformational mobility of tissue inhibitor of metalloproteinases-2 (TIMP-2). Journal of Biological Chemistry, 274 (52). pp. 37226-37232. ISSN 0021-9258. The full text of this publication is not available from this repository.

Butler, G.S. and Hutton, M. and Wattam, B.A. and Williamson, R.A. and Knauper, V. and Willenbrock, F. and Murphy, G.H. (1999) The specificity of TIMP-2 for matrix metalloproteinases can be modified by single amino acid mutations. Journal of Biological Chemistry, 274 (29). pp. 20391-20396. ISSN 0021-9258. The full text of this publication is not available from this repository.

Hutton, M. and Butler, G.S. and Wattam, B.A. and Willenbrock, F. and Williamson, R.A. and Murphy, G. (1999) Analysis of the interaction of TIMP-2 and MMPs: engineering the changes. Annals of the New York Academy of Sciences, 878 . pp. 524-527. ISSN 0077-8923 . The full text of this publication is not available from this repository.

Glaser, M. and Howard, M.J. and Howland, K. and Powell, A.K. and Rae, M.T. and Wocadlo, S. and Williamson, R.A. and Blower, P.J. (1998) Structural characterisation and bioconjugation of an active ester containing oxorhenium(V) complex incorporating a thioether donor. Journal of the Chemical Society-Dalton Transactions (18). pp. 3087-3092. ISSN 0300-9246. The full text of this publication is not available from this repository.

Muskett, F.W. and Frenkiel, T.A. and Feeney, J. and Freedman, R.B. and Carr, M.D. and Williamson, R.A. (1998) High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3. J Biol Chem, 273 (34). pp. 21736-21743. ISSN 0021-9258. The full text of this publication is not available from this repository.

Williamson, R.A. and Carr, M.D. and Frenkiel, T.A. and Feeney, J. and Freedman, R.B. (1997) Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation. Biochemistry, 36 (45). pp. 13882-13889. ISSN 0006-2960. The full text of this publication is not available from this repository.

Williamson, R.A. and Natalia, C. and Gee, C.K and Murphy, G.H. and Carr, M.D. and Freedman, R.B. (1996) Chemically and conformationally authentic active domain of human tissue inhibitor of metalloproteinases-2 refolded from bacterial inclusion bodies. European Journal of Biochemistry, 241 (2). pp. 476-483. ISSN 0014-2956. The full text of this publication is not available from this repository.

Williamson, R.A. and Martorell, G. and Carr, M.D. and Murphy, G.H. and Docherty, A.J.P. and Freedman, R.B. and Feeney, J. (1994) Solution Strucure of the Active Domain of Tissue Inhitor of Metalloprotrinases.2.A new Member of the OB Fold Protein Family. Biochemistry, 33 (39). pp. 11745-11759. ISSN 0006-2960. The full text of this publication is not available from this repository.

Williamson, R.A. and Bartels, H. and Murphy, G.H. and Freedman, R.B. (1994) Folding and Stability of the Active N-Terminal Domain of Tissue Inhibitor of Metalloproteinse-1 and Metalloproteinase-1 and Metalloproteinase-2. Protein Engineering, 7 (8). pp. 1035-1040. ISSN 0269-2139. The full text of this publication is not available from this repository.

Williamson, R.A. and Bartels, H. and Murphy, G. and Freedman, R.B. (1994) Folding and stability of the active N-terminal domain of tissue inhibitor of metalloproteinases-1 and -2. Protein Eng, 7 (8). pp. 1035-1040. ISSN 0269-2139 . The full text of this publication is not available from this repository.

Williamson, R.A. and Smith, B.J and Angal, S. and Freedman, R.B. (1993) Chemical modification of tissue inhibitor of metalloproteinases-1 and its inactivation by diethyl pyrocarbonate. Biochimica Et Biophysica Acta, 1203 (1). pp. 147-154. ISSN 0006-3002. The full text of this publication is not available from this repository.

Williamson, R.A. and Smith, B.J. and Angal, S. and Murphy, G. and Freedman, R.B. (1993) Structural analysis of tissue inhibitor of metalloproteinases-1 (TIMP-1) by tryptic peptide mapping. Biochimica Et Biophysica Acta, 1164 (1). pp. 8-16. ISSN 0006-3002. The full text of this publication is not available from this repository.

Oshea, M. and Willenbrock, F. and Williamson, R.A. and Cockett, M.I. and Freedman, R.B. and Reynolds, J.J. and Docherty, A.J.P. and Murphy, G. (1992) Site-Directed Mutations That Alter the Inhibitory Activity of the Tissue Inhibitor of Metalloproteinases-1 - Importance of the N-Terminal Region between Cysteine-3 and Cysteine-13. Biochemistry, 31 (42). pp. 10146-10152. ISSN 0006-2960. The full text of this publication is not available from this repository.

Murphy, G. and Houbrechts, A. and Cockett, M.I. and Williamson, R.A. and O'Shea, M. and Docherty, A.J.P. (1991) The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity. Biochemistry, 30 (33). pp. 8097-8102. ISSN 0006-2960 . The full text of this publication is not available from this repository.

Williamson, R.A. and Marston, F.A. and Angal, S. and Koklitis, P. and Panico, M. and Morris, H.R. and Carne, A.F. and Smith, B.J. and Harris, T.J. and Freedman, R.B. (1990) Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP). Biochemical Journal, 268 (2). pp. 267-274. ISSN 0264-6021 . The full text of this publication is not available from this repository.

Datasets / databases

Rowe, M.L. and Ruddock, L.W. and Kelly, G. and Schmidt, J.M. and Williamson, R.A. and Howard, M.J. (2009) Solution structure of Oxidised ERp18. RSCB/PDB Protein Data Bank PDB formatted text file. 8.1MB. Located at: http://www.rcsb.org/pdb/explore/explore.do?pdbId=2K8V. 10.2210/pdb2k8v/pdb. The full text of this publication is not available from this repository.

Rowe, M.L. and Alanen, H.I. and Ruddock, L.W. and Kelly, G. and Schmidt, J.M. and Williamson, R.A. and Howard, M.J. (2009) 1H, 13C, 15N chemical shift assignments for oxidised ERp18. Biological Magnetic Resonance Data Bank (BMRB), Madison, Wisconsin, USA NMR-STAR formatted text file. 102kB. Located at: http://www.bmrb.wisc.edu/data_library/generate_summary.php?bmrbId=15964. BMRB entry 15964. The full text of this publication is not available from this repository.

Rowe, M.L. and Alanen, H.I. and Ruddock, L.W. and Kelly, G. and Schmidt, J.M. and Williamson, R.A. and Howard, M.J. (2009) 1H, 13C, 15N chemical shift assignments for reduced ERp18. Biological Magnetic Resonance Data Bank (BMRB), Madison, Wisconsin, USA NMR-STAR formatted text file. 53kB. Located at: http://www.bmrb.wisc.edu/data_library/generate_summary.php?bmrbId=7430. BMRB entry 7430. The full text of this publication is not available from this repository.

This list was generated on Sat May 18 09:09:00 2013 BST.