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Number of items: 45.

Article

Hooker, Andrew D. and Goldman, Merlin H. and Markham, Nicola H. and James, David C. and Ison, Andrew P. and Bull, Alan T. and Strange, Philip G. and Salmon, Ian and Baines, Anthony J. and Jenkins, Nigel (2007) N-Glycans of Recombinant Human Interferon-Gamma Change During Batch Culture of Chinese - Hamster Ovary Cells. Biotechnology and Bioengineering, 97 (2). pp. 410-424. ISSN 0006-3592. (doi:https://doi.org/10.1002/bit.260480612) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Underhill, Michele F. and Smales, Christopher Mark and Naylor, Louise H. and Birch, John R. and James, David C. (2007) Transient Gene Expression Levels from Multigene Expression Vectors. Biotechnology Progress, 23 (2). pp. 435-443. ISSN 8756-7938. (doi:https://doi.org/10.1021/bp060225z) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Underhill, Michele F. and Marchant, Rosalyn J. and Carden, Martin J. and James, David C. and Smales, Christopher Mark (2006) On the effect of transient expression of mutated eIF2 alpha and eIF4E eukaryotic translation initiation factors on reporter gene expression in mammalian cells upon cold-shock. Molecular Biotechnology, 34 (2). pp. 141-149. ISSN 1073-6085. (doi:https://doi.org/10.1385/MB:34:2:141) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Dinnis, Diane M. and Stansfield, Scott H. and Schlatter, Stefan and Smales, Christopher Mark and Alete, Daniel E. and Birch, John R. and Racher, Andrew J. and Marshal, Carol T. and Nielsen, Lars K. and James, David C. (2006) Functional proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate. Biotechnology and Bioengineering, 94 (5). pp. 830-841. ISSN 0006-3592. (doi:https://doi.org/10.1002/bit.20899) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Weeks, Mark E. and von Caron, G.N. and James, David C. and Smales, Christopher Mark and Robinson, Gary K. (2006) Monitoring changes in nisin susceptibility of Listeria monocytogenes Scott A as an indicator of growth phase using FACS. Journal of Microbiological Methods, 66 (1). pp. 43-55. ISSN 0167-7012. (doi:https://doi.org/10.1016/j.mimet.2005.10.008) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Ahmad, Norhaiza and Zhang, Jian and Brown, Philip J. and James, David C. and Birch, John R. and Racher, Andrew J. and Smales, Christopher Mark (2006) On the statistical analysis of the GS-NS0 cell proteome: Imputation, clustering and variability testing. Biochimica Et Biophysica Acta-Proteins and Proteomics, 1764 (7). pp. 1179-1187. ISSN 1570-9639. (doi:https://doi.org/10.1016/j.bbapap.2006.05.002) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Alete, Daniel E. and Racher, Andrew J. and Birch, John R. and Stansfield, Scott H. and James, David C. and Smales, Christopher Mark (2005) Proteomic analysis of enriched microsomal fractions from GS-NS0 murine myeloma cells with varying secreted recombinant monoclonal antibody productivities. Proteomics, 5 (18). pp. 4689-4704. ISSN 1615-9853. (doi:https://doi.org/10.1002/pmic.200500019) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Dinnis, Diane M. and Stansfield, Scott H. and Alete, Daniel E. and Sage, E.A. and Birch, John R. and Racher, Andrew J. and Marshall, Carol T. and James, David C. (2004) Comparative proteomic analysis of GS-NSO murine myeloma cell lines with varying recombinant monoclonal antibody production rate. Biotechnology and Bioengineering, 88 (4). pp. 474-488. ISSN 0006-3592. (doi:https://doi.org/10.1002/bit.20272) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
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Weeks, Mark E. and James, David C. and Robinson, Gary K. and Smales, Christopher Mark (2004) Global changes in gene expression observed at the transition from growth to stationary phase in Listeria monocytogenes ScottA batch culture. Proteomics, 4 (1). pp. 123-135. ISSN 1615-9853. (doi:https://doi.org/10.1002/pmic.200300527) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
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Underhill, Michele F. and Coley, Clare and Birch, John R. and Findlay, Alison and Kallmeier, Robert and Proud, Christopher G. and James, David C. (2003) Engineering mRNA translation initiation to enhance transient gene expression in chinese hamster ovary cells. Biotechnology Progress, 19 (1). pp. 121-129. ISSN 8756-7938. (doi:https://doi.org/10.1021/bp025560b) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Birch, John R. and Racher, Andrew J. and Marshall, Carol T. and James, David C. (2003) Evaluation of individual protein errors in silver-stained two-dimensional gels. Biochemical and Biophysical Research Communications, 306 (4). pp. 1050-1055. ISSN 0006-291X. (doi:https://doi.org/10.1016/S0006-291X(03)01115-X) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Harris, Lucy C. and Davis, Paul J. and James, David C. (2003) Fatty acids as haptens: exploring the limits of antigenicity. Molecular Immunology, 40 (6). pp. 381-389. ISSN 0161-5890. (doi:https://doi.org/10.1016/S0161-5890(03)00150-0) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Baker, Kym N. and Rendall, Mark H. and Patel, A. and Boyd, Paul and Hoare, Michael and Freedman, Robert B. and James, David C. (2002) Rapid monitoring of recombinant protein products: a comparison of current technologies. Trends Biotechnol, 20 (4). pp. 149-156. ISSN 0167-7799. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Pepper, Duncan S. and James, David C. (2002) Protein modification during anti-viral heat-treatment bioprocessing of factor VIII concentrates, factor IX concentrates, and model proteins in the presence of sucrose. Biotechnology and Bioengineering, 77 (1). pp. 37-48. ISSN 0006-3592. (doi:https://doi.org/10.1002/bit.10161) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided)
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Hills, Anna E. and Patel, Ashvin and Boyd, Paul and James, David C. (2001) Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells. Biotechnology and Bioengineering, 75 (2). pp. 239-251. ISSN 0006-3592. (doi:https://doi.org/10.1002/bit.10022) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Pepper, Duncan S. and James, David C. (2001) Protein Modifications during Antiviral Heat Bioprocessing and Subsequent Storage. Biotechnology Progress, 17 (5). pp. 974-978. ISSN 8756-7938. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Baker, Kym N. and Rendall, Mark H. and Hills, Anna E. and Hoare, Michael and Freedman, Robert B. and James, David C. (2001) Metabolic Control of Recombinant Protein N-glycan Processing in NS0 and CHO Cells. Biotechnology and Bioengineering, 73 (3). pp. 188-202. ISSN 0006-3592. (doi:https://doi.org/10.1002/bit.1051) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Pepper, Duncan S. and James, David C. (2001) Evaluation of Protein Modification during Anti-Viral Heat Bioprocessing by Electrospray Ionization Mass Spectrometry. Rapid Communications in Mass Spectrometry, 15 (5). pp. 351-356. ISSN 0951-4198. (doi:https://doi.org/10.1002/rcm.232) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Davis, Paul J. and Smales, Christopher Mark and James, David C. (2001) How can Thermal Processing Modify the Antigenicity of Proteins? Allergy, 56 (s67). pp. 56-60. ISSN 0105-4538. (doi:https://doi.org/10.1034/j.1398-9995.2001.00918.x) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Pepper, Duncan S. and James, David C. (2000) Mechanisms of protein modification during model anti-viral heat-treatment bioprocessing of beta-lactoglobulin variant A in the presence of sucrose. Biotechnology and Applied Biochemistry, 32 (2). pp. 109-119. ISSN 0885-4513. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hills, Anna E. and Patel, Ashvin and Boyd, Paul and James, David C. (2000) Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells. Glycobiology, 10 (10). p. 1108. ISSN 0959-6658. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hooker, Andrew D. and James, David C. (2000) Analysis of glycoprotein heterogeneity by capillary electrophoresis and mass spectrometry. Molecular Biotechnology, 14 (3). pp. 241-249. ISSN 1073-6085. (doi:https://doi.org/10.1385/MB:14:3:241) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Smales, Christopher Mark and Pepper, Duncan S. and James, David C. (2000) Protein modification during antiviral heat bioprocessing. Biotechnology and Bioengineering, 67 (2). pp. 177-188. ISSN 0006-3592. (doi:https://doi.org/10.1002/(SICI)1097-0290(20000120)67:2<177::AID-BIT7>3.0.CO;2-3) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hooker, Andrew D. and Green, Nicola H. and Baines, Anthony J. and Bull, Alan T. and Jenkins, Nigel and Strange, Philip G. and James, David C. (1999) Constraints on the transport and glycosylation of recombinant IFN-gamma in Chinese hamster ovary and insect cells. Biotechnology and Bioengineering, 63 (5). pp. 559-572. ISSN 0006-3592. (doi:https://doi.org/10.1002/(SICI)1097-0290(19990605)63:5<559::AID-BIT6>3.0.CO;2-L) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Lagutin, Oleg V. and Dobrovolsky, Vasily N. and Vinogradova, T.V. and Kyndiakov, B.N. and Khodarovich, Y.M. and Jenkins, Nigel and James, David C. and Markham, Nicola H. and Larionov, Oleg A. (1999) Efficient human IFN-gamma expression in the mammary gland of transgenic mice. Journal of Interferon and Cytokine Research, 19 (2). pp. 137-144. ISSN 1079-9907. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

James, David C. and Freedman, Robert B. and Hoare, Michael and Ogonah, Olotu W. and Rooney, Barrie C. and Larionov, Oleg A. and Dobrovolsky, Vasily N. and Lagutin, Oleg V. and Jenkins, Nigel (1998) N-Glycosylation of Recominant Human Interferon-Gamma Produced in Deferent Animal Expression System. Biotechnology and Bioengineering, 60 (5). pp. 59-607. ISSN 0006-3592. (doi:https://doi.org/10.1002/(SICI)1097-0290(19981205)60:5<596::AID-BIT10>3.0.CO;2-) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hooker, Andrew D. and James, David C. (1998) The glycosylation heterogeneity of recombinant human IFN-gamma. Journal of Interferon and Cytokine Research, 18 (5). pp. 287-295. ISSN 1079-9907. (doi:https://doi.org/10.1089/jir.1998.18.287) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Jenkins, Nigel and Hooker, Andrew D. and James, David C. (1998) Measurement of intracellular glycans on recombinant glycoproteins. Abstracts of Papers of the American Chemical Society, 216 . 246-BIOT. ISSN 0065-7727. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Goldman, Merlin H. and James, David C. and Rendall, Mark H. and Ison, Andrew P. and Hoare, Michael and Bull, Alan T. (1998) Monitoring recombinant human interferon-gamma n-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells. Biotechnology and Bioengineering, 60 (5). pp. 596-607. ISSN 0006-3592. (doi:https://doi.org/10.1002/(SICI)1097-0290(19981205)60:5<596::AID-BIT10>3.0.CO;2-5) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Goldman, Merlin H. and James, David C. and Ison, Andrew P. and Bull, Alan T. (1997) Monitoring proteolysis of recombinant human interferon-? during batch culture of Chinese hamster ovary cells. Cytotechnology, 23 (1-3). pp. 103-111. ISSN 0920-9069. (doi:https://doi.org/10.1023/A:1007947130709) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Goldman, Merlin H. and James, David C. and Ison, Andrew P. and Bull, Alan T. (1997) Monitoring proteolysis of recombinant human interferon-gamma during batch culture of Chinese hamster ovary cells. Cytotechnology, 23 (1-3). pp. 103-111. ISSN 0920-9069. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

James, David C. (1996) Analysis of recombinant glycoproteins by mass spectrometry. Cytotechnology, 22 (1-3). pp. 17-24. ISSN 0920-9069. (doi:https://doi.org/10.1007/BF00353920) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

James, David C. and Goldman, Merlin H. and Hoare, Michael and Jenkins, Nigel and Oliver, Ronald W. A. and Green, Brian N. and Freedman, Robert B. (1996) Posttranslational processing of recombinant human interferon-gamma in animal expression systems. Protein Science, 5 (2). pp. 331-340. ISSN 0961-8368. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

James, David C. and Freedman, Robert B. and Hoare, Michael and Jenkins, Nigel (1994) High-Resolution Separation of Recombinant Human Interferon-Gamma Glycoforms by Micellar Electrokinetic Capillary Chromatography. Analytical Biochemistry, 222 (2). pp. 315-322. ISSN 0003-2697. (doi:https://doi.org/10.1006/abio.1994.1498) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Book section

Alete, Daniel E. and Racher, R.J. and Birch, John R. and James, David C. and Smales, Christopher Mark (2005) The functional competence of animal cells: Analysis of the secretory pathway. In: Godia, Francesc and Fussenegger, Martin M., eds. Animal Cell Technology Meets Genomics. ESACT Proceedings, 2 . Springer, Dordrecht, pp. 71-74. ISBN 978-1-4020-2791-8. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Conference or workshop item

Baker, Kym N. and Johnson, I.D. and Roberts, G. and Cook, A. and Baines, Anthony J. and Gerardy-Schahn, R. and James, David C. (1999) Metabolic engineering of recombinant plasminogen sialylation in animal cells by tetracycline-regulated expression of murine CMP-NeuAc synthetase and hamster CMP-NeuAc transporter genes. In: Bernard, Alain and Griffiths, Bryan and Noe, W. and Wurm, Florian, eds. Animal Cell Technology: Products from Cells, Cells as Products. ESACT Meeting. Springer Netherlands, Netherlands pp. 263-265. ISBN 0-7923-6075-3. (doi:https://doi.org/10.1007/0-306-46875-1_60) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hills, Anna E. and Patel, A.K. and Boyd, Paul and James, David C. (1999) Control of therapeutic monoclonal antibody glycosylation. In: 16th Meeting of the European-Society-for-Animal-Cell-Technology (ESACT), Apr 25-29, 1999, Lugano, Switzerland. (doi:https://doi.org/10.1007/0-306-46875-1_58) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Heaton, Michele and Birch, John R. and Hovey, Alison and Kallmeier, Robert and Proud, Christopher G. and James, David C. (1999) Genetic manipulation of the protein synthetic capacity of mammalian cells. In: 16th Meeting of the European-Society-for-Animal-Cell-Technology (ESACT), Apr 25-29, 1999, Lugano, Switzerland. (doi:https://doi.org/10.1007/0-306-46875-1_5) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Baker, Kenneth C. and Ison, Andrew P. and Freedman, Robert B. and Jones, David Wynne and James, David C. (1997) Real-time monitoring of recombinant protein concentration in animal cell cultures using an optical biosensor. In: Genetic Engineer and Biotechnologist. pp. 69-74. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Green, Nicola H. and Hooker, Andrew D. and James, David C. and Baines, Anthony J. and Strange, Philip G. and Jenkins, Nigel and Bull, Alan T. (1997) Control of interferon-gamma glycosylation by the addition of defined lipid supplements to batch cultures of recombinant Chinese hamster ovary cells. In: Funatsu, K. and Shirai, Y. and Matsushita, T., eds. Animal Cell Technology: Basic & Applied Aspects. Kluwer Academic Publ pp. 339-345. ISBN 0-7923-4486-3. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hooker, Andrew D. and Green, Nicola H. and James, David C. and Strange, Philip G. and Baines, Anthony J. and Bull, Alan T. and Jenkins, Nigel (1997) Epitope determination for antibodies raised against recombinant human interferon-gamma. In: 14th Meeting of the ESACT on Animal Cell Technology - From Vaccines to Genetic Medicine, May 1996, Vilamoura, Portugal. (doi:https://doi.org/10.1007/978-94-011-5404-8_43) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Hooker, Andrew D. and Goldman, Merlin H. and Green, Nicola H. and James, David C. and Bull, Alan T. and Strange, Philip G. and Baines, Anthony J. and Jenkins, Nigel (1997) Resolution glycoform analysis of recombinant human interferon-gamma during batch cultures of Chinese hamster ovary cells. In: 8th Annual Meeting of the Japanese-Association-for-Animal-Cell-Technology, Nov 06-10, 1995, Iizuka, Japan. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Goldman, Merlin H. and Bull, Alan T. and Ison, Andrew P. and James, David C. and Jenkins, Nigel (1995) A Comparison of 2 Electrophoretic Methods for Analysing Recombinant Protein Glycoforms. In: 1995 Icheme Research Event - First European Conference for Young Researchers in Chmical Engineering. Inst Chemical Engineers pp. 896-898. ISBN 0-85295-359-3. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Edited book

Smales, Christopher Mark and James, David C., eds. (2005) Characterization of therapeutic proteins by membrane and in-gel tryptic digestion. Methods in Molecular Biology, 308 . Humana Press, 482 pp. ISBN 978-1-58829-390-9. (doi:https://doi.org/10.1385/1-59259-922-2:375) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

Review

Jenkins, Nigel and Parekh, R.B. and James, David C. (1996) Getting the glycosylation right: Implications for the biotechnology industry. Nature Biotechnology, 14 (8). pp. 975-981. ISSN 1087-0156. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

This list was generated on Sat May 11 18:32:04 2019 BST.